Internal Medicine

0521779407-14 CUNY1086/Karliner 0 521 77940 7 June 4, 2007 21:16

998 Molluscum Contagiosum Motor Neuron Diseases

tests

■Biopsy is confirmatory.

■Potassium hydroxide preparation often reveal molluscum bodies.

differential diagnosis

■Clinically characteristic

■In immunosuppressed patients, cryptococcal infection may mas-

querade as molluscum.

management

What to Do First

■Establish diagnosis.

■Examine contacts.

General Measures

■Assess for other sexually transmitted diseases in adults.

specific therapy

■Removal or destruction – liquid nitrogen, sharp curettage or laser

ablation

follow-up

■Reassess for recurrences at 2–3 months following the last observed

lesion.

complications and prognosis

■Self-limited disease except in immunocompromised patients

MOTOR NEURON DISEASES

MICHAEL J. AMINOFF, MD, DSc

history & physical

■Diffuse weakness, w/o sensory or sphincter disturbance

➣Spinal muscular atrophy: lower motor neuron deficit mainly in

limbs

➣Primary lateral sclerosis: upper motor neuron deficit in limbs

➣Progressive bulbar palsy: lower motor neuron deficit in bulbar

muscles