Internal Medicine

0521779407-18 CUNY1086/Karliner 0 521 77940 7 June 13, 2007 8:1

1284 Renal Calculi Renal Glucosuria

■hyperuricosuria: allopurinol, limited intake of animal protein

■hypocitraturia: K citrate

■hyperoxaluria: vitamin B6, low-oxalate diet

■low urine pH: K citrate

■cystinuria: K citrate and chelating agents

■infection stones: stone removal, suppressive antibiotics, rarely ure-

ase inhibitor

complications and prognosis

■recurrent stones: without medical prophylaxis, risk of recurrence at

least 50% within 5 years

■renal failure from untreated, obstructing stones or staghorn calculi

■infection: due to obstruction or presence of infection stones

RENAL GLUCOSURIA

MICHEL BAUM, MD

history & physical

■Glucosuria found in asymptomatic patient on routine urinalysis

■No history of polydipsia, polyuria, or polyphagia

tests

■Urinalysis positive for glucose

■Normal blood glucose and hemoglobin A1c

■Normal electrolytes and serum phosphorus

differential diagnosis

■Autosomal recessive disorder due to inactivating mutation of Na-

glucose cotransporter (SGLT2) in proximal tubule

management

n/a

specific therapy

■No therapy indicated

follow-up

n/a

complications and prognosis

Prognosis excellent