Internal Medicine

(Wang) #1

0521779407-18 CUNY1086/Karliner 0 521 77940 7 June 4, 2007 21:20


1314 RSV/Respiratory Syncytial Virus Rubella

management
■For hospitalized patients – contact precautions are recommended
for duration of illness
■Good hand washing should be emphasized.
specific therapy
■In uncomplicated case – no treatment needed
■Ribavarin aerosol therapy may be considered for CHD, BPD, cys-
tic fibrosis, and underlying immunodeficiency. Controversial in
children; data to suggest that it reduces mortality in adults post BMT.
■RSV-IVIG may also be effective in certain high-risk patients.

follow-up
n/a
complications and prognosis
■infants/young children –
➣important cause bronchiolitis and pneumonia
➣apnea can occur in preterm and <1-month-old infants
■High severity in infants with CHD, immunodeficiency, underlying
pulmonary disease
■Exacerbation of asthma any age group

RUBELLA


CAROL A. GLASER, MD


history & physical
History
■aka “German measles” or 3-day measles
■Togaviridae, RNA virus
■Transmission usually respiratory route, direct contact or droplet
(congenital infection also possible)
■Incubation 16–18 days (14–23 days)
■Humans only host
■Maximal communicability: few days BEFORE and 5–7 days after
ONSET rash
■Late winter/spring – peak incidence

Signs & Symptoms
■25–50% infections asymptomatic
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