Internal Medicine

(Wang) #1

0521779407-22 CUNY1086/Karliner 0 521 77940 7 June 4, 2007 21:23


1510 Vaginitis Valvular Heart Disease Aortic Stenosis (AS)

➣For persistent/recurrent symptoms, re-examine and repeat ther-
apy with longer course of topical therapy, different topical agent
or oral therapy if topical originally used; consider infection with
non-albicans candida
➣Consider treatment of sexual partner; review hygiene
➣For recurrent VVC (defined as≥4 episodes of symptomatic dis-
ease per year), screen for diabetes and HIV; consider gynecolog-
ical referral and long-term antifungal suppression therapy
■Trichomoniasis
➣Treatment with Metronidazole results in cure rates of 90–95%
➣Recurrent infections caused by organisms with decreased sus-
ceptibility to Metronidazole can usually be treated with higher
doses
➣Associated with premature rupture of membranes and preterm
delivery but routine screening in pregnancy not generally rec-
ommended

VALVULAR HEART DISEASE AORTIC STENOSIS (AS)


JUDITH A. WISNESKI, MD


history & physical
Etiology
■Congenital bicuspid aortic valve (develops AS ages 40–60; more com-
mon in males)
■Senile calcified (normal 3 – leaflet valve; AS ages 70–80)
■Rheumatic heart disease (abnormality of mitral valve present)
■Congenital AS

History
■Symptoms of pulmonary congestion: PND, DOE or orthopnea (due
to left ventricular (LV) diastolic impairment or systolic dysfunction)
■Angina (may be related to LV hypertrophy alone, or in combination
with CAD)
■Syncope/near-syncope – usually associated with exertion (due to
limited cardiac output secondary to aortic valve obstruction, vasode-
pressor response, or stress induced arrhythmia)

Signs & Symptoms
■Systolic murmur radiates to the right supraclavicular fossa
➣Mild to moderate AS: Murmur peaks early in systole
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