Science - USA (2022-04-08)

GRAPHIC: A. MASTIN/

SCIENCE

SCIENCE science.org 8 APRIL 2022 • VOL 376 ISSUE 6589 109

180 Plant science

TaCol-B5 modifies spike architecture and

enhances grain yield in wheat X. Zhang et al.

PERSPECTIVE p. 133

184 Optics

Topological engineering of terahertz light

using electrically tunable exceptional point

singularities M. S. Ergoktas et al.

188 Biomaterials

Mineralization generates megapascal

contractile stresses in collagen fibrils

H. Ping et al.

PERSPECTIVE p. 137

193 Graphene

Orderly disorder in magic-angle twisted

trilayer graphene S. Turkel et al.

199 Physics

Measurement of a helium tune-out

frequency: an independent test of quantum

electrodynamics B. M. Henson et al.

203 Nanomaterials

Three-dimensional visualization of

nanoparticle lattices and multimaterial

frameworks A. Michelson et al.

ON THE COVER

Symbolic illustration of the W boson

weighing down on the standard model of

particle physics. The mass of the W boson,

a mediator of the weak nuclear force, is tightly

constrained by the theory. A new, very-high-

precision measurement of the W boson

mass is in significant tension with the standard

model expectation

and suggests that

improvements

to calculations or

extensions to the

standard model might

be needed. See pages

125, 136, and 170.

Illustration: Carlo Cadenas

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DEPARTMENTS

111 Editorial

New goals for science philanthropy

By F. A. Córdova

210 Working Life

In search of plan B, I found plan A

By A. Hughes

New Products ............................................ 208

Science Careers ........................................ 209

RESEARCH

IN BRIEF

148 From Science and other journals

REVIEW

151 Nanomaterials

High-entropy nanoparticles:

Synthesis-structure-property relationships

and data-driven discovery Y. Ya o et al.

REVIEW SUMMARY; FOR FULL TEXT:

DOI.ORG/10.1126/SCIENCE.ABN

138 & 156

CONTENTS

BOOKS E T A L.

141 Investing in what matters most

Faced with a family crisis, a marine scientist

finds parallels with Earth’s imperiled coral

reefs By S. M. Johnson

142 Gender, biology, and behavior

There is much to learn from a primatologist’s

framework for gender diversity By B. J. King

LETTERS

144 Spain’s Doñana World Heritage

Site in danger

By J. G. Navedo et al.

144 US conservation atlas needs

biodiversity data

By C. Carroll et al.

145 Life in science: Drifting away

in the Atlantic

By E. Sampaio

PRIZE ESSAY

146 Biomaterials for boosting

food security

Renewable silk-protein technologies promote

plant growth and reduce food waste

By B. Marelli

RESEARCH ARTICLES

152 Cancer genomics

Genome-wide analysis of somatic noncoding

mutation patterns in cancer F. Dietlein et al.

RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:

DOI.ORG/10.1126/SCIENCE.ABG

Immunogenomics

153 Single-cell RNA-seq reveals cell

type–specific molecular and genetic

associations to lupus R. K. Perez et al.

RESEARCH ARTICLE SUMMARY; FOR FULL

TEXT: DOI.ORG/10.1126/SCIENCE.ABF

154 Single-cell eQTL mapping identifies

cell type–specific genetic control of

autoimmune disease S. Yazar et al.

RESEARCH ARTICLE SUMMARY; FOR FULL

TEXT: DOI.ORG/10.1126/SCIENCE.ABF

PERSPECTIVE p. 134

155 Protein engineering

Tuning T cell receptor sensitivity through

catch bond engineering X. Zhao et al.

RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:

DOI.ORG/10.1126/SCIENCE.ABL

156 Virome

Cryptic and abundant marine viruses at the

evolutionary origins of Earth’s RNA virome

A. A. Zayed et al.

PERSPECTIVE p. 138; PODCAST

163 Structural biology

Structure of a Janus kinase cytokine receptor

complex reveals the basis for dimeric

activation C. R. Glassman et al.

PERSPECTIVE p. 139

170 Particle physics

High-precision measurement of the W boson

mass with the CDF II detector CDF Collaboration

NEWS STORY p. 125; PERSPECTIVE p. 136

REPORTS

176 Developmental biology

Functional primordial germ cell–like cells

from pluripotent stem cells in rats

M. Oikawa et al.