Small Animal Dermatology, 3rd edition

370 DISEASES/DISORDERS

VDC-1101: double prodrug of PMEG; administered with prednisone in 12 dogs

demonstrated efficacy to induce remission or to reduce lesions

Consultation with a veterinary oncologist or dermatologist for treatment options

recommended.

COMMENTS

 Prognosis for CnEL: remission may be achieved in 80% of dogs; median survival time

depends on type/form of lymphoma; range 2 months to years.

 Prognosis for CEL: guarded to grave; cure is extremely unlikely unless a solitary, early

lesion can be surgically excised: median survival time for dogs depends on stage of

disease at diagnosis, therapeutic choice, and response to therapy; varies from weeks to

longer than 18 months; dogs and cats may live for longer than 2 years after diagnosis

(rarely).

 The goal is to maintain a good quality of life for as long as possible.

 Radiation therapy: total skin electron beam therapy (TSEBT) or orthovoltage radia-

tion is well tolerated and may be beneficial in some cases.

 Death is usually the result of euthanasia.

Synonyms

 Lymphoma, epidermotropic

 Mycosis fungoides

Fig. 24.1.Multiple irregular to arciform, erythematous to purpuric nodules, characteristic of CnEL, in a 14-
year-old female-spayed Jack Russell terrier.