412 DISEASES/DISORDERS
are better managed with divided twice-daily dosing; if receiving insulin twice daily,
trilostane should be given to coincide with insulin administration; effective in cats
with no reported side effects; decreases clinical signs of HAC; improves regulation of
diabetes but may not resolve diabetes.Precautions/Interactions
Hyperadrenocorticism: closely monitor diabetic cat; adjust insulin to prevent hypo-
glycemia when the cortisol levels fall.
Fig. 27.1.Generalized poor hair coat and distended belly appearance of a 16-year-old male-castrate DSH
with naturally acquired hyperadrenocorticism. Note alopecia of and epidermal injury at the base of the left pinna.
Fig. 27.2.Closer image of alopecia and a healing epidermal tear at the base of the left pinna of patient in
Figure 27.1.