• Ability of B-cells to present antigen to helper T-cells is
a second function of B-cells in response to antigenic
stimulation other than differentiating into antibody-
secreting plasma cells.
• B-cells process antigen and present it to helper T cells
in the same way as described for dendritic cells and
macrophages.
• The activated T helper cells then activate B-cells and a
subgroup of T-cells called T cytotoxic cells in a specific
manner.
• The activated B-cells and T cytotoxic cells divide
repeatedly to produce clone of cells.
• All the cells of a clone recognize the same antigen and
fight it, neutralize its action and eliminate it.
Immune response
• The specific reactivity induced in a host by an antigenic
stimulus is known as the immune response.
• It is of two types :
- Primary immune response : It is the reaction of
the body’s immune system to the first attack of
microbes (antigens) and takes much longer time
to develop. - Secondary immune response : It is the reaction
of the body’s immune system to any subsequent