Supplemental Figures
Figure S1. Cryo-EM Raw Data and Reference Structures, Related toFigure 2
(A) Med-PIC cryo-electron tomography reference structure (Cryo-ET) shown alongside the refined single-particle cryo-EM map (Cryo-SP) as reference.
(B) EMAN2 starting model derived from small group of 2D class averages used to generate an initial model in Relion using unsupervised 3D particle classification.
Both reference structures are shown alongside the refined Med-PIC map.
(C) Representative Med-PIC particles imaged in vitreous ice with 100 nm scale-bar included as size reference.