Figure 7. Selected IGHV1-202/IGKV3-2001 IgGs Cloned from the Stepwise Immunized Mice Neutralized the Same Viruses Sensitive to the
Corresponding Mouse Sera
Neutralization IC 50 and IC 80 of the 27 IgGs against Env-pseudoviruses 45-01dG5, 426c, the mutant 426c viruses lacking one, two, or all three glycans at aa 276,
460 and 463, and 247-23 were listed. The presence (+) or absence () of N276/460/463 glycans in each pseudovirus is indicated. The neutralizing titers of VRC01
were shown as positive controls.
See alsoFigure S7.
Cell 166 , 1471–1484, September 8, 2016 1481