The Human Brain During the Third Trimester

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Insular
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Cerebellar
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Cere bellar
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Spinal cord


Medulla


O C C I P I T A L L O B E


PARACENTRAL


LOBULE


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PART VI:


GW30


HORIZONT AL


PART VI:


GW30


HORIZONT AL


Figure 7. Lateral view of a GW30 brain with major structures in the cerebral hemispheres labeled. (From the
photographic series of: J. C. Larroche (1967) Maturation morphologique du système nerveux central: ses rap-
ports avec le développement pondéral du foetus et son age gestationnel. In: Regional Development of the Brain
in Early Life, A. Minkowski (ed.), London: Blackwell, page 248.)

This specimen is case number W-187-65 (Perinatal RPSL) in the


Yakovlev Collection. A male infant survived 17 hours after a premature


birth. Death occurred because of a pulmonary hyaline membrane.


Autopsy notes include a subarachnoid hemorrhage over the cerebrum,


but the brain appears normal and is classified as a Normative Control


in the Yakovlev Collection (Haleem, 1990). It was cut in the horizontal


plane in 35-μm thick sections. Since there is no available photograph


of this brain before it was embedded and cut, we use the lateral view of


another GW30 brain that Larroche published in 1967 (Figure 7).


The approximate cutting plane of this brain is indicated in Figure 8


(facing page) with lines superimposed on the GW30 brain from the Lar-


roche (1967) series. The anterior part of each section is ventral to the


posterior part. As in all other specimens, the sections chosen for illustra-


tion are more closely spaced to show small structures in the diencepha-


lon, midbrain, pons, and medulla. Illustrated sections are spaced farther


apart when they contain only large brain structures, such as the cerebral


cortex, basal ganglia, and cerebellum. Photographs of 24 different Nissl-


stained sections (Levels 1-24) are shown at low magnification in Plates


112-131. The core of the brain and the cerebellum are shown at high


magnification in companion Plates 132AB-150AB for Levels 3-24.

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