The Human Brain During the Third Trimester

Bed nucleusof the stria

terminalis

Bed nucleusof the stria

terminalis

FFrroonnttaall^ lloobbee

Interhemispheric

fissure

White matter

Cortical plate

Layer I

Cingulate

gyrus

Cingulate

gyrus

SEPTUMSEPTUM

PREOPTIC

AREA

PREOPTIC

AREA

BASAL

GANGLIA

BA SAL

GANGLIA

C

a

u

d

a

te

(^) n
u
cle
u
s (h
ea
d
)
C
a
u
d
a
te
(^) n
u
cle
u
s (h
ea
d
)
TTe mporal lobeemporal lobe
Lateral fissure
Inte
rnal capsule (anterior limb)
Inte
rn
al capsule (anterior limb)
PutamenPutamen
Inferior temporal
gyrus
Inferior temporal
gyrus
Inferior frontal
gyrus
Inferior frontal
gyrus
Olfactory
tubercle
Olfactory
tuberc le
Callosal glioepithelium
Lateral migratory stream
(infiltrates claustrum and
penetrates insular cortex)
Lateral migratory stream
(extends to olfactory tubercle)
Lateral migratory stream
(extends to olfactory tubercle)
Lateral migratory stream
(extends to temporal cortex)
Lateral migratory stream
(extends to temporal cortex)
Strionuclear glioepitheliumStrionuclear glioepithelium
Ventral
striatum
Ve ntral
striatum

C

in

g

ulu

m

C

in

g

ulu

m

AAnntteerriioorr ccoommmmiissssuurree

Induseum

griseum

Third ve ntricle

(preoptic recess)

Glial migration?

(into optic chiasm)

Suprachiasmatic nucleus

Sexually dimorphic nucleus?

Medial prMedial preoptic nucleuseoptic nucleus??

Lateral

preoptic

area

Lateral

preoptic

Medial area

preoptic

area

Medial

preoptic

area

Median

preoptic

nucleus

Median

preoptic

nucleus

Magnocellular

preoptic

nucleus

(part of the

horizontal limb

of diagonal band)

PPerieriventricular prventricular preoptic nucleuseoptic nucleus

Lateral olfactory tract

Endopiriform

nucleus

Endopiriform

nucleus

Cave of the

septum

Cave of th e

septum

Stria

terminalis

Stria

terminalis

Uncinate

fasciculus

Uncinate

fasciculus

I

n

s

u

al

r

g

y

r

u

s

I

n

s

u

al

r

g

y

r

u

s

C

al

u

s

tr

u

m

C

al

u

s

tr

u

m

Substan

tiai

nno

min

ata

Substan

tiai

nno

min

ata

Islands of CallejaIslands of Calleja??

Abnormal

hemorrhage in the

germinal matrix

Abnormal

hemorrhage in the

germinal matrix

Fornix

(column)

Fornix

(column)

Lateral septal

nucleus

Lateral septal

nucleus

FFornixornix

Optic chiasmOptic chiasm

Anterior

commissure

Anterior

commissure

CCoorrppuussccaalllloossuumm((bbooddyy))

Diagonal band of Broca

(horizontal limb)

Diagonal band of Broca

(horizontal limb)

P

r

i

m

a

r

y

o

lf

ac

to

ry

co

rtex

(p

iri

fo

rm

)

P

r

i

m

a

r

y

o

lf

ac

to

ry

co

rtex

(p

iri

fo

rm

)

E

x

te

r

n

a

l

c

a

p

us

le

E

x

te

r

n

a

l

c

a

p

us

le

La

te

ra

l v

en

tr

icle

FFr ontal stratified transitional fielrontal stratified transitional fieldd

Frontal neuroepithelium

and subventricular zone

Fr ontal neuroepithelium

and subventricular zone

Pr

im

ary

olfa

ctory

cortex(pi

r

if

o

r

m

)

Pr

im

ary

olfa

ctory

cortex(pi

r

if

o

r

m

)

Lateral migratory stream

(infiltrates endopiriform nucleus

and penetrates piriform cortex)

Lateral migratory stream

(infiltrates endopiriform nucleus

and penetrates piriform cortex)

Subpial

granular layer

Fornical

glioepithelium

Fo rnical

glioepithelium

Anterolateral striatal neuroepithelium

and subventricular zone

Anterolateral striatal neuroepithelium

and subventricular zone

Anteromedial striatal neuroepithelium

and subventricular zone

Anteromedial striatal neuroepithelium

and subventricular zone

Septal

glioepithelium/

ependyma

Septal

glioepithelium/

ependyma

Preoptic

glioepithelium/

ependyma

Preoptic

glioepithelium/

ependyma

Germinal and transitional structures in italics

ChorChoroid plexusoid plexus

Fusiform

gyrus

Fusiform

gyrus

Middle temporal

gyrus

Middle temporal

gyrus

Superior temporal

gyrus

Superior temporal

gyrus

Anterior

amygdaloid

area?

Anterior

amygdaloid

area?

Parolfactory/

parahippocampal

gyrus

Parolfactory/

parahippocampal

gyrus

Globus pallidus

(external segment)

Globus pallidus

(external segment)

Callosal slingCallosal sling

PLATE 176B