The Human Brain During the Third Trimester

Oculomotor

nuclear

complex (III)

Oculomotor

nuclear

complex (III)

Nodulus

X

Nodulus

X

Uvula

IX

Uvula

IX

Pyramis

VIII

Pyramis

VIII

Folium

VIIa

Fo lium

VIIa

Declive

VI

Declive

VI

Culmen

IV, V

Culmen

Lingula IV, V

I, II

Lingula

I, II

Centralis

III

Centralis

III

Tuber

VIIb

Tuber

VIIb

Oculomotor nerve (III)

Ce

re

br

al

(^) p
ed
un
cle
Ce
re
br
al
(^) p
ed
un
cle
Mammillary
body
Mammillary
body
Third ventricle
Fornix (post-
commissural)
Fornix (post-
commissural)
FFornixornix
Ca
ve of th
e
septu
m
Choroid
plexus
Choroid
plexus
Choroid
plexus
Choroid
plexus
Corpus
callosum
(splenium)
Corpus
callosum
(splenium)
HYPO-
THALAMUS
HYPO-
THALAMUS
SEPTUMSEPTUM
MIDBRAIMIDBRAINN
PONSPONS
Inferior
colliculus
Inferior
colliculus
Reticular
formation
Reticular
fo rmation
Reticular
formation
Reticular
fo rmation
Medial longitudinal fasciculus
and tectospinal tract
Pontocerebellar fibers
(thin transverse bundles)
Middle
cerebellar
peduncle
Ve ntral funiculus (spinal cord)
Central canal (spinal cord)
Ependyma
Gracile fasciculus
Dorsal motor nucleus (X)
Dorsal sensory nucleus (X)
Inter-
peduncular
nucleus
Inter-
peduncular
nucleus

F

ourth ventricle

Gracile nucleus

TEGMENTUMTEGMENTUM

TECTUMTECTUM

Brachium of the inferior colliculus

Optic nerve layer

Posterior commissure

Stria medullaris and

habenulo-interpeduncular tract

Stria medullaris and

habenulo-interpeduncular tract

Medial habenular

nucleus?

Fastigial

nucleus

Fa stigial

nucleus

INFERIOR

LOBE

INFERIOR

LOBE

POSTERIOR

LOBE

POSTERIOR

LOBE

V E R M I SV E R M I S

Preculminate fissure

A (separates centralis and culmen)

Primary fissure

B (separates anterior and central lobes)

Secondary fissure

(separates central and posterior

lobes)

D

Prepyramidal fissure

C (separates tuber and pyramis)

Po sterolateral fissure

(separates posterior and inferior

lobes)

E

Cerebellar fissu res

CC

AA

BB

BB

CC

DD

DD

EE

EE

*Raphe nuclear complex

Superior

cerebellar

peduncle

Superior

cerebellar

peduncle

H

yp

og

lo

ss

al

(^) n
u
cl
eu
s
(X
II
)
H
yp
og
lo
ss
al
(^) n
u
cl
eu
s
(X
II
)
C
E
N
T
R
A
L
L
O
B
E
C
E
N
T
R
A
L
L
O
B
E
Superior
colliculus
Superior
colliculus
Central
gray
Central
gray
MEDULLAMEDULLA

SPISPINNAL CORDAL CORD

A

N

T

E

RI

OR LO

BE

A

N

T

E

RI

OR LO

BE

Pontine

gray

Pontine

gray

*Arcuate nucleus

(medulla)

Optic

chiasm

Optic

chiasm

Suprachiasmatic nucleuSuprachiasmatic nucleuss

Olfactory peduncle

Diagonal band of Broca

(vertical limb)

Diagonal band of Broca

(vertical limb)

Induseum

griseum

TTe nia tecta?enia tecta?

Red

nucleus

Red

nucleus

Forel's

fields

Fo rel's

fields

THALAMUS

ANTERIOR COMPLEX

THALAMUS

ANTERIOR COMPLEX

Medial lemniscusMedial lemniscus

Anterior commissuAnterior commissurree

Bed nucleus of the

stria terminalis?

Stria medullarisStria medullaris

Central

nucleus

Central

nucleus

Gyrus Gyrus rrectuectuss

Cingulate gyrusCingulate gyrus

Medial prMedial preoptic nucleueoptic nucleuss

Supraoptic nucleuSupraoptic nucleuss

Pyramidal

decussation

Pyramidal

decussation

Su

pe

rio

rc

er

eb

ella

rpeduncle

Su

pe

rio

rc

er

eb

ella

rpeduncle

Corpus callosum

(genu)

Corpus callosum

(genu)

C

or

p

us

c

al

lo

su

m

(b

od

y)

C

or

p

us

c

al

lo

su

m

(b

od

y)

PREOPTIC

AREA

PREOPTIC

AREA

11

11

4

4

2

5

3

3

7

8

13

13

13

12

1111

9

10

14

14

Medial

lemniscus

Medial

lemniscus

Pyramid (corticospinal tract)

CEREBELLUMCEREBELLUM

Medial

septal nucleus

Medial

septal nucleus

CingulumCingulum

Reticular

tegmental

nucleus

Reticular

tegmental

nucleus

Locus

coeruleus

Locus

coeruleus

Dorsal

longitudinal

fasciculus

Dorsal

longitudinal

fasciculus

Abcucens

nucleus (VI)

Abcucens

nucleus (VI)

Dorso-

medial

nucleus

Dorso-

medial

nucleus

Substantia

nigra

Substantia

nigra

Habenulo-

interpeduncular

tract

Habenulo-

interpeduncular

tract

Dorsal

tegmental

nucleus

Dorsal

tegmental

nucleus

Ventro-

medial

nucleus

Ve ntro -

medial

nucleus

M

ed

ial

lo

ng

itu

di

na

lfa

sci

cu

lu

s

M

ed

ial

lo

ng

itu

di

na

lfa

sci

cu

lu

s

Remnants of the germinal matrix,

migratory streams, and transitional fields

1 Rostral migratory stream

2 Callosal sling?

Cortical

plate

White

matter

Layer I

Transpontine corticofugal tract

(thick longitudinal bundles)

3 Callosal glioepithelium

4 Fo rnical glioepithelium

5 Strionuclear glioepithelium

6 Thalamic glioepithelium/ependyma

7 Mesencephalic glioepithelium/ependyma

8 Pontine glioepithelium/ependyma

9 Medullary glioepithelium/ependyma

10 Cerebellar glioepithelium/ependyma

11 Raphe migration

13 External germinal layer

12 Germinal trigone

14 Subpial granular layer

6

Hi

ppo

cam

pal

comm

issure

Hi

ppo

cam

pal

comm

issure

F

o

rn

ix

(p

re

co

m

m

iss

ur

al

)

F

o

rn

ix

(p

re

co

m

m

iss

ur

al

)

Damaged areas in section

*Infiltrated by

the Raphe migration

PLATE 201B