The Human Brain During the Third Trimester

H

I

P

P O C A M P U S

H

I

P

P O C A M P U S

Subiculum

Dentate gyrus

Ammon's horn

Entorhinal

cortex

Lateral vLateral ventriclentriclee

Temporal

lobe

Te mporal

lobe

Frontal

lobe

Frontal

lobe

Lateral migratory stream

(infiltrating the endopiriform nucleus

and entering the piriform cortex,

temporal cortex, and amygdala)

Rostral migratory streaRostral migratory streamm

Lateral fissure

Layer I

Layer II

Layer III

Layer IV

Layers V- VI

Subpial granular layerSubpial granular layer

Cortical plate

White matter

Orbital gyrusOrbital gyrus

Gyrus Gyrus rrectuectuss

Pontine

glioepithelium/

ependyma

Pontine

glioepithelium/

ependyma

Primary

fissure

Pyramis

(VIII)

Pyramis

(VIII)

Uvula?

(IX)

Uvula?

(IX)

De

nta

te^ n

ucle

us

De

nta

te^ n

ucle

us

Sim

ple

x lo

bu

le

(H

VI

)

Sim

ple

x lo

bu

le

(H

VI

)

Lateral lemniscus

Nucleus of the lateral

lemniscus (dorsal)

Suprachiasmatic nucleuSuprachiasmatic nucleuss

VVe ntromedial nucleuentromedial nucleuss

Mammillary

body

Mammillary

body

Lateral tuberal nucleuLateral tuberal nucleuss

Fourth

ventricle

Fourth

ventricle

HYPOHYPOTHALAMUSTHALAMUS

A M Y G D A L A

A M Y G D A L A

CEREBELLAR CEREBELLAR VERMISVERMIS

CEREBELLAR

HEMISPHERE

CEREBELLAR

HEMISPHERE

Parahippocampal

gyrus

Parahippocampal

gyrus

Subgranular zoneSubgranular zone

External

germinal

layer

Inter-

peduncular

nucleus

Inter-

peduncular

nucleus

Locus

coeruleus

Locus

coeruleus

Parabrachial

nucleus

Parabrachial

nucleus

Abducens

nucleus (VI)

Abducens

nucleus (VI)

Raphe nuclear complexRaphe nuclear complex

Su

pe

ri

or

(^) c
er
eb
el
la
r
pe
du
nc
le
(^) (d
ec
us
sa
tio
n)
Su
pe
ri
or
(^) c
er
eb
el
la
r
pe
du
nc
le
(^) (d
ec
us
sa
tio
n)
C
er
e
br
al
pe
dun
cle
C
er
e
br
al
pe
dun
cle
EndopiriEndopirifform nucleuorm nucleuss
Primary olfactory cortex (pirifPrimary olfactory cortex (piriform)orm)
Lateral olfactory tractLateral olfactory tract
Medial longitudinal fasciculuMedial longitudinal fasciculuss
Baso-
lateral
complex
Baso-
lateral
complex
Co
rtic
om
edi
al
com
plex
Co
rtic
om
edi
al
com
plex
Amygdalo-
hippocampal
area?
Amygdalo-
hippocampal
area?

A

nte

rio

r lo

be

(H

I-H

V)

A

nte

rio

r lo

be

(H

I-H

V)

S

ub

st

an

tia

n

ig

ra

S

ub

st

an

tia

n

ig

ra

M

ID

B

R

AI

NT

EGM

ENT

UM

Reticular

formation

Reticular

formatio n

Paramedian

lobule?

(HVIIB)

Paramedian

lobu le?

(HVIIB)

Optic tract

Arcuate nucleus

Lamina terminalis

Olfactory

peduncle

Olfactory

peduncle

Oculomotor

nerve (III)

Interpositus

nucleus

Interpositus

nucleus

Fastigial

nucleus

Fa stigial

nucleus

Infe

rio

rc

ere

be

lla

rpe

dun

cle

Infe

rio

rc

ere

be

lla

rpe

dun

cle

S

u

pe

ri

orcerebella

rp

ed

uncle

S

u

pe

ri

orcerebella

rp

ed

uncle

PONTINE

TEGMENTUM

PONTINE

TEGMENTUM

C E R E B E L

L

A

R

D

E

E

P

NU

CL

EI

C E R E B E L

L

A

R

D

E

E

P

NU

CL

EI

M

ed

ia

ll

em

ni

scu

s?

M

ed

ia

ll

em

ni

scu

s?

Third ventricle

(mammillary recess)

Third ventricle

(mammillary recess)

Parahippocampal neuroepithe-

lium, subventricular zone, and

stratified transitional field

Pa rahippocampal neuroepithe-

lium, subventricular zone, and

stratified transitional field

AlvAlve ar glioepitheliuear glioepitheliumm

Te mporal stratified transitional field

Te mporal neuroepithelium and subventricular zone

Damaged area

Germinal and transitional

structures in italics

Germinal and transitional

structures in italics

Inferior temporal gyrusInferior temporal gyrus

Diencephalic

(hypothalamic)

glioepithelium/

ependyma

Diencephalic

(hypothalamic)

glioepithelium/

ependyma

Amygdaloid

glioepithelium/ependyma

Amygdaloid

glioepithelium/ependyma

Ansiform

lobule

(Crus II HVIIA)

Ansiform

lobu le

(Crus II HVIIA)

Ansiform

lobule

(Crus I HVIIA)

Ansiform

lobu le

(Crus I HVIIA)

Myelination

gliosis

Myelination

gliosis

PLATE 237B

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