HUMAN BIOLOGY

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342 Chapter 17

Birth and Beyond


The hormonal flood is triggered by an as-yet-unknown
signal that says, in effect, it’s time to be born. The placenta
responds to the fetal hormones by producing more estro-
gen. Rising estrogen in turn calls for a rush of oxytocin and
of prostaglandins (also produced by the placenta), which
jointly stimulate uterine con tractions. For about the next
2 to 18 hours, the contractions will become stronger, more
painful, and more frequent.

Labor has three stages


Labor is divided into three stages that we can think of
loosely as “before, during, and after.” In the first stage,
uterine contractions push the fetus against its mother’s
softened cervix. Initial contractions occur about every
15 to 30 minutes and are relatively mild. As the cervix
gradually dilates to a diameter of about 10 centimeters
(4 inches, or “5 fingers”), contractions become more fre-
quent and intense. Usually, the amniotic sac ruptures dur-
ing this stage, which can last 12 hours or more.
The second stage of labor, actual birth of the fetus,
typically occurs less than an hour after the cervix is fully
dilated. This stage is usually brief—under 2 hours. Strong
contractions of the uterus and abdominal muscles occur
every 2 or 3 minutes, and the mother feels an urge to push.
Her efforts and the intense contractions move the soon-
to-be newborn through the cervix and out through the
vaginal canal, usually head first (Figure 17.16). Complica-
tions can develop if the baby begins to emerge in a breech
position—that is, if a body part other than the head is exit-
ing first. In that case the doctor may use hands or forceps
to aid the delivery.
After the baby is born, the third stage of labor gets
under way. More uterine contractions force fluid, blood,
and the placenta (now called the afterbirth) from the moth-
er’s body. The umbilical cord—the lifeline to the mother—
is now severed. A lifelong reminder of this separation is
the scar we call the navel, the site where the umbilical cord
was attached.
Without the placenta to remove wastes, carbon dioxide
builds up in the baby’s blood. Together with other factors,
including handling by medical personnel, this stimulates
control centers in the brain, which respond by triggering
inhalation—the newborn’s crucial first breath.
As the infant’s lungs begin to function, the bypass ves-
sels of the fetal circulation begin to close, soon to shut
completely. The fetal heart opening, the foramen ovale,
normally closes slowly during the first year of life.
Most full-term pregnancies end in the birth of a
healthy infant. Yet babies born prematurely—especially
before about 8 months of intrauterine life—can suffer
complications because their organs have not developed

n    Birth, or parturition, takes place about 280 days from the
start of the woman’s last menstrual period.
n Link to Hormones of the hypothalamus and pituitary 15.3

maternal changes and fetal hormones set
the stage for childbirth
A pregnancy is considered “full term” about 39 weeks
after fertilization. A few weeks before this point, changes
occur that set the stage for childbirth. To begin with, col-
lagen fibers in the connective tissue of the cervix loosen.
The once-rigid cervix gradually softens so it can stretch
to allow the fetus to pass from the uterus into the birth
canal. Expectant mothers often are keenly aware of another
change—the “drop” of the fetus as it shifts to a lower posi-
tion in the uterus, usually head-down.
The birth process, or labor, begins when smooth muscle
in her uterus starts to contract. These contractions are the
indirect result of a cascade of hor-
mones from the fetus’s hypothala-
mus, pituitary, and adrenal glands.

dilating cervix

placenta

wall of uterus
umbilical cord

placenta detaching
from wall of uterus

umbilical cord

F i g u r e 17.16 During birth, the fetus is pushed out of the uterus.
The afterbirth—the placenta, fluid, and blood—is expelled shortly
afterward. (© Cengage Learning)

1 7. 9


labor The birth process.


1 Fetus positioned
for childbirth; its
head is against the
mother’s cervix,
which is dilating
(widening).

2 Muscle contrac-
tions stimulated by
oxytocin force the
fetus out through the
vagina.

3 The placenta
detaches from the
wall of the uterus
and is expelled.

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