95
Jung DW, Kim WH, Williams DR (2014) Reprogram or reboot: small molecule approaches for the
production of induced pluripotent stem cells and direct cell reprogramming. ACS Chem Biol
9:80–95
Juopperi TA, Song H, Ming GL (2011) Modeling neurological diseases using patient-derived
induced pluripotent stem cells. Future Neurol 6:363–373
Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K (2009) Virus-free induction of
pluripotency and subsequent excision of reprogramming factors. Nature (Lond) 458:771–775
Kitamura T, Koshino Y, Shibata F, Oki T, Nakajima H, Nosaka T, Kumagai H (2003) Retrovirus-
mediated gene transfer and expression cloning: powerful tools in functional genomics. Exp
Hematol 31:1007–1014
Kumar D, Talluri TR, Anand T, Kues WA (2015) Induced pluripotent stem cells: mechanisms,
achievements and perspectives in farm animals. World J Stem Cells 7:315–328
Kunisada Y, Tsubooka-Yamazoe N, Shoji M, Hosoya M (2012) Small molecules induce effi cient
differentiation into insulin-producing cells from human induced pluripotent stem cells. Stem
Cell Res 8:274–284
Liu H, Zhu F, Yong J, Zhang P, Hou P, Li H, Jiang W, Cai J, Liu M, Cui K et al (2008) Generation
of induced pluripotent stem cells from adult rhesus monkey fi broblasts. Cell Stem Cell
3:587–590
Loh YH, Agarwal S, Park IH, Urbach A, Huo H, Heffner GC, Kim K, Miller JD, Ng K, Daley GQ
(2009) Generation of induced pluripotent stem cells from human blood. Blood 113:
5476–5479
Lu HF, Narayanan K, Lim SX, Gao S, Leong MF, Wan AC (2012) A 3D microfi brous scaffold for
long-term human pluripotent stem cell self-renewal under chemically defi ned conditions.
Biomaterials 33:2419–2430
Ludwig TE, Levenstein ME, Jones JM, Berggren WT, Mitchen ER, Frane JL, Crandall LJ, Daigh
CA, Conard KR, Piekarczyk MS et al (2006) Derivation of human embryonic stem cells in
defi ned conditions. Nat Biotechnol 24:185–187
Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu
J, Jaenisch R et al (2007) Directly reprogrammed fi broblasts show global epigenetic remodel-
ing and widespread tissue contribution. Cell Stem Cell 1:55–70
Martin GR (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in
medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 78:7634–7638
Mathur A, Loskill P, Shao K, Huebsch N, Hong S, Marcus SG, Marks N, Mandegar M, Conklin
BR, Lee LP et al (2015) Human iPSC-based cardiac microphysiological system for drug
screening applications. Sci Rep 5:8883
Mehta A, Verma V, Nandihalli M, Ramachandra CJA, Sequiera GL, Sudibyo Y, Chung Y, Sun W,
Shim W (2014) A systemic evaluation of cardiac differentiation from mRNA reprogrammed
human induced pluripotent stem cells. PLoS One 9, e103485
Mei Y, Saha K, Bogatyrev SR, Yang J, Hook AL, Kalcioglu ZI, Cho SW, Mitalipova M, Pyzocha
N, Rojas F et al (2010) Combinatorial development of biomaterials for clonal growth of human
pluripotent stem cells. Nat Mater 9:768–778
Meng G, Liu S, Rancourt DE (2012) Synergistic effect of medium, matrix, and exogenous factors
on the adhesion and growth of human pluripotent stem cells under defi ned, xeno-free condi-
tions. Stem Cells Dev 21:2036–2048
Minami I, Yamada K, Otsuji TG, Yamamoto T, Shen Y, Otsuka S, Kadota S, Morone N, Barve M,
Asai Y et al (2012) A small molecule that promotes cardiac differentiation of human pluripo-
tent stem cells under defi ned, cytokine- and xeno-free conditions. Cell Rep 2:1448–1460
Miyoshi K, Tsuji D, Kudoh K, Satomura K, Muto T, Itoh K, Noma T (2010) Generation of human
induced pluripotent stem cells from oral mucosa. J Biosci Bioeng 110:345–350
Nagy A (2000) Cre recombinase: the universal reagent for genome tailoring. Genesis 26:99–109
Nagy K, Sung HK, Zhang P, Lafl amme S, Vincent P, Agha-Mohammadi S, Woltjen K, Monetti C,
Michael IP, Smith LC et al (2011) Induced pluripotent stem cell lines derived from equine
fi broblasts. Stem Cell Rev 7:693–702
4 New Trends in Clinical Applications of Induced Pluripotent Stem Cells