Stem Cell Processing (Stem Cells in Clinical Applications)

vii

Contents

1 Stem Cell Therapy: Accepted Therapies, Managing the Hope
of Society, and a Legal Perspective ........................................................ 1
W. M. Botes , M. Nöthling Slabbert , M. Alessandrini ,
and M. S. Pepper

2 Mesenchymal Stem Cells in Clinical Applications ............................... 37
Phuc Van Pham

3 Ageing and Senescence in Mesenchymal Stem Cells ........................... 71
Hitesh D. Tailor , Yiannis Pengas , and Wasim S. Khan

4 New Trends in Clinical Applications of Induced Pluripotent
Stem Cells ................................................................................................ 77
Phuc Van Pham , Nhan Lu-Chinh Phan , Ngoc Bich Vu ,
Nhung Hai Truong , and Ngoc Kim Phan

5 The Effects of Ageing on Proliferation Potential,
Differentiation Potential and Cell Surface Characterisation
of Human Mesenchymal Stem Cells ...................................................... 99
Emma Fossett , Yiannis Pengas , and Wasim S. Khan

6 Production of Clinical-Grade Mesenchymal Stem Cells ..................... 107
Phuc Van Pham and Ngoc Bich Vu

7 Isolation and Characterization of Adipose- Derived
Stromal Cells ........................................................................................... 131
Fiona A. van Vollenstee , Carla Dessels , Karlien Kallmeyer ,
Danielle de Villiers , Marnie Potgieter , Chrisna Durandt ,
and Michael S. Pepper

8 Cord Blood Stem Cell Banking .............................................................. 163
Helen C. Steel , Marco Alessandrini , Juanita Mellet ,
Carla Dessels , Ahmed K. Oloyo , and Michael S. Pepper