114
Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ (1997)
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk
regulation through Cdc25. Science 277(5331):1497–1501
Santamaria D, Barriere C, Cerqueira A, Hunt S, Tardy C, Newton K, Caceres JF, Dubus P,
Malumbres M, Barbacid M (2007) Cdk1 is sufficient to drive the mammalian cell cycle. Nature
448(7155):811–815. doi:10.1038/nature06046
Santos F, Hendrich B, Reik W, Dean W (2002) Dynamic reprogramming of DNA methylation in
the early mouse embryo. Dev Biol 241(1):172–182. doi:10.1006/dbio.2001.0501
Santos SD, Wollman R, Meyer T, Ferrell JE Jr (2012) Spatial positive feedback at the onset of
mitosis. Cell 149(7):1500–1513. doi:10.1016/j.cell.2012.05.028
Sasaki K, Shima H, Kitagawa Y, Irino S, Sugimura T, Nagao M (1990) Identification of members
of the protein phosphatase 1 gene family in the rat and enhanced expression of protein phos-
phatase 1 alpha gene in rat hepatocellular carcinomas. Jpn J Cancer Res 81(12):1272–1280
Satinover DL, Leach CA, Stukenberg PT, Brautigan DL (2004) Activation of Aurora-A kinase by
protein phosphatase inhibitor-2, a bifunctional signaling protein. Proc Natl Acad Sci U S A
101(23):8625–8630. doi:10.1073/pnas.0402966101
Schmidt A, Duncan PI, Rauh NR, Sauer G, Fry AM, Nigg EA, Mayer TU (2005) Xenopus polo-
like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity. Genes Dev 19(4):502–
- doi:10.1101/gad.320705
Schmitz MH, Held M, Janssens V, Hutchins JR, Hudecz O, Ivanova E, Goris J, Trinkle-Mulcahy
L, Lamond AI, Poser I, Hyman AA, Mechtler K, Peters JM, Gerlich DW (2010) Live-cell
imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regula-
tors in human cells. Nat Cell Biol 12(9):886–893. doi:10.1038/ncb2092
Sents W, Ivanova E, Lambrecht C, Haesen D, Janssens V (2013) The biogenesis of active protein
phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity.
FEBS J 280(2):644–661. doi:10.1111/j.1742-4658.2012.08579.x
Sheng J, Kumagai A, Dunphy WG, Varshavsky A (2002) Dissection of c-MOS degron. EMBO
J 21(22):6061–6071
Shi Y (2009) Serine/threonine phosphatases: mechanism through structure. Cell 139(3):468–484.
doi:10.1016/j.cell.2009.10.006
Shima H, Hatano Y, Chun YS, Sugimura T, Zhang Z, Lee EY, Nagao M (1993) Identification of
PP1 catalytic subunit isotypes PP1 gamma 1, PP1 delta and PP1 alpha in various rat tissues.
Biochem Biophys Res Commun 192(3):1289–1296
Shimura T, Toyoshima M, Taga M, Shiraishi K, Uematsu N, Inoue M, Niwa O (2002) The novel
surveillance mechanism of the Trp53-dependent s-phase checkpoint ensures chromosome
damage repair and preimplantation-stage development of mouse embryos fertilized with
x- irradiated sperm. Radiat Res 158(6):735–742
Shindo M, Nakano H, Kuroyanagi H, Shirasawa T, Mihara M, Gilbert DJ, Jenkins NA, Copeland
NG, Yagita H, Okumura K (1998) cDNA cloning, expression, subcellular localization, and
chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1
and 2. Biochem Biophys Res Commun 244(1):285–292. doi:10.1006/bbrc.1998.8250
Shoji S, Yoshida N, Amanai M, Ohgishi M, Fukui T, Fujimoto S, Nakano Y, Kajikawa E, Perry AC
(2006) Mammalian Emi2 mediates cytostatic arrest and transduces the signal for meiotic exit
via Cdc20. EMBO J 25(4):834–845. doi:10.1038/sj.emboj.7600953
Shteinberg M, Protopopov Y, Listovsky T, Brandeis M, Hershko A (1999) Phosphorylation of the
cyclosome is required for its stimulation by Fizzy/cdc20. Biochem Biophys Res Commun
260(1):193–198. doi:10.1006/bbrc.1999.0884
Sikora-Polaczek M, Hupalowska A, Polanski Z, Kubiak JZ, Ciemerych MA (2006) The first mito-
sis of the mouse embryo is prolonged by transitional metaphase arrest. Biol Reprod 74(4):734– - doi:10.1095/biolreprod.105.047092
Stanevich V, Jiang L, Satyshur KA, Li Y, Jeffrey PD, Li Z, Menden P, Semmelhack MF, Xing Y
(2011) The structural basis for tight control of PP2A methylation and function by LCMT-1.
Mol Cell 41(3):331–342. doi:10.1016/j.molcel.2010.12.030
A. Heim et al.