••• Chapter 43^ Cervical Lesions and Cancer^439
❍ What is the 5-year survival rate of patients undergoing pelvic exenteration for recurrent cervical cancer?
With careful patient selection, up to 50%.
❍ What is the incidence of long-term response to cisplatin when used for advanced or recurrent cervical cancer?
Overall response to cisplatin is 25%. However, long-term response is generally not seen.
❍ Match the following characteristics to the appropriate histologic subtype of cervical cancer.
(1) Histologically similar to oat cell cancer of the lung Clear cell carcinoma (c)
(2) Radiation may induce a more malignant transformation Small cell neuroendocrine tumors (a)
(3) Associated with DES exposure Verrucous carcinoma (b)
(4) Associated with Peutz–Jeghers syndrome Minimal deviation adenocarcinoma (adenoma
malignum) (d)