512 Obstetrics and Gynecology Board Review •••
❍ How often is primary adenocarcinoma of the tube bilateral?
One in five cases.
❍ What is the prognosis in tubal adenocarcinoma?
It is quite poor with about 30% survival at 5 years.
❍ A patient has an ulcerative lesion on the vulva and you are told that microscopically there are Donovan
bodies. What are those and what is the disease and organism?
The disease is granuloma inguinale that is caused by Calymmatobacterium granulomatis. The Donovan bodies are
vacuolated macrophages that are filled with the organism and are seen with the aid of a Giemsa stain.
❍ By dark-field examination, you are able to detect spirochete organisms taken from a painless ulcer from the
genitalia of a female. What is your diagnosis?
Syphilis (Treponema pallidum).
❍ Where in the process of cell division are the oocytes of the ovary at the time of birth?
They are in a resting stage of the first meiotic division. They will not complete that process until ovulation and
fertilization occur.
❍ In a primary follicle of an infant, what are the cells that lie around the oocyte?
Granulosa cells.
❍ What is a Call-Exner body?
This is a small, round collection of eosinophilic material that is surrounded by a ring of granulosa cells. These are
normal but can be seen in granulosa cell tumors of the ovary.
❍ What is the primary source of estrogen in the preovulatory stage of menses?
The theca cells.
❍ What is the primary source of progesterone in the ovary that is responsible for regulation of the secretory
phase of menses?
The corpus luteum.
❍ If fertilization occurs, when does primary production of progesterone no longer occur in the corpus luteum?
After about 8 weeks, the placenta begins taking over primary production of progesterone from the corpus luteum.
❍ What is the name of the benign, non-neoplastic cystic lesion of the ovary that occurs as a result of
invagination of the cortex and surface epithelium?
Epithelial inclusion cyst.
❍ At what age do solitary follicle cysts and corpus luteum cysts occur?
The solitary follicle cysts occur in perimenopausal women and after menarche, while corpus luteum cysts occur in
women of childbearing age.