Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical, Part 1

(Elle) #1

22


Abbreviations


MET metabolic exercise training


LV left ventricle


RV right ventricle


LA left atrium


RA right atrium


AoR aortic root


ECG electrocardiography


HCM hypertrophic cardiomyopathy


DCM dilated cardiomyopathy


ARVC arrhytmogenic right ventricular cardiomyopathy


TDI tissue Doppler imaging


RBBB right bundle branch block


TAPSE tricuspid annular plane systolic excursion


PASP pulmonary arterial systolic pressure


CMR cardiac magnetic resonance


PTAC pulmonary transit of agitated contrast


BSA body surface area


LAVI left atrial volume indexed


TNF-α tumor necrosis factor-α


STE speckle tracking echocardiography


BAV bicuspid aortic valve


The physical exercise leads many benefits, especially, in reducing the cardiovascular


risk and in improving quality and expectancy of life. It has been demonstrated that


the regular physical exercise reduces of about 30% the cardiovascular risk in healthy


people [ 1 ]. Moreover, long term regular exercise training determines, especially in


elite athletes, several cardiac structural changes, which represent the “athlete’s heart”,


characterized by bradycardic rhythm at rest and enlarged cardiac chambers [ 2 ].


The current recommended regular physical exercise of 150  min per week of

moderate physical exercise is far from developing the athlete’s heart. Its develop-


ment occurs in athletes that regularly perform 20 h of intense exercise (15 METs)


per week to participate to competitive races. Cardiac adaptations of the “athlete’s


heart” is affected by many factors as the ethnicity, genetic, age, sex, and type, inten-


sity and duration of exercise. Physical activity determine an increased stroke vol-


ume and enhanced diastolic filling also at high heart rates, reduction of vascular


resistance and of heart rate due to the improvement of vagal tone and reduction of


sympathetic tone. Isotonic or endurance sports (for example walking, running,


swimming and skiing) are characterized by aerobic work and long distance exer-


cise. In acute phase of endurance exercise, there is an increase of cardiac output,


maximum oxygen consumption and peripheral vasodilatation in order to satisfy the


A. D’Andrea et al.
Free download pdf