platform. (LGPC, Université de La
Rochelle, France).
Figure 9.15 Stability test realised at
80°C of Novozym 435 after
optimisation of operational parameters
for a propionic acid alkyl ester
synthesis under reduced pressure.
by a considerable reduction of the volumes that have to be treated compared to liquid
organic systems.
Numerous applications should benefit from this technology. The on line bio-treatment
of waste gases for toxic removal or modification (Uchiyama et al., 1992; Zilli et al.,
1992; Davison and Thompson, 1993) is already envisaged, since it is clear that high
catalytic efficiency is possible with very short residence time in the solid/gas reactor.
However, this step represents the next bottleneck to overcome, since it implies the
maintenance of multiple enzymatic activity and cofactor regeneration systems.
ACKNOWLEDGMENTS
The authors wish to thank the E.U. for their financial support within the framework of a
demonstration project (BIO4–CT98–0390).
REFERENCES
Multiphase bioreactor design 284