CHAPTER
6
Reflecting
Questions
The Endocrine System
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When a gymnastic performer
entertains us with a display of
prolonged, intense physical activity,
the performer’s body is being pushed
to the limits of its capabilities. During
the performance, homeostatic
mechanisms work to maintain the
body’s internal environment within
tolerance limits — the narrow range
of conditions within which cellular
processes are able to function at a
normal level.
The endocrine system works in
parallel with the nervous system to
maintain homeostasis. It does so by
releasing chemical substances —
hormones – which in turn trigger
actions in specific target cells. For
example, vigorous exercise triggers
endocrine glands in the brain and
elsewhere to release several different
hormones. These hormones regulate
oxygen consumption, basal metabolic
rate, and the metabolizing of
carbohydrates and fat for energy. As a
result, the rate and depth of breathing
increase, as do heart rate and muscle
contraction. In addition, energy stores
are quickly mobilized. These changes
ensure that fuel is readily available
for an increase in skeletal muscle,
heart, and brain activity, while at the
same time maintaining normal
physiological processes.
In this chapter, you will learn
about the components of the
endocrine system. You will examine
how the nervous system and the
endocrine system interact to regulate
physiology, and how these systems
affect each other’s functions. You will
also explore how, in addition to
maintaining homeostasis, the
endocrine system regulates a wide
range of other biological processes.
These processes include thecontrol
of blood sugar, metabolism, growth,
reproductive development and
function, and other physiological
activities. You will discover how the
body responds to stress, and how
abnormal endocrine function can
result in disease. Finally, you will see
how some major endocrine disorders
can be treated.
Endocrine glands within the brain
secrete hormones to influence
metabolism in other target glands.
This positron emission tomography
(PET) scan relies on a radioactive
tracer, injected into the bloodstream,
to reveal the brain’s metabolic activity.
How does the nervous
system interact with and
regulate endocrine activity?
How do endocrine
hormones maintain
homeostasis in the body?
What are some of the
major treatable diseases
of the human endocrine
system?
Prerequisite
Concepts
and Skills
Before you begin this chapter,
review the following concepts
and skills:
distinguishing between
the structure and
properties of protein and
lipid molecules (Chapter 1,
section 1.2),
explaining the concepts of
homeostasis and dynamic
equilibrium (Chapter 4,
section 4.1),
explaining the difference
between negative and
positive feedback loops
(Chapter 4, section 4.1).
explaining how the
kidneys control water
balance in the body
(Chapter 4, section 4.2),
describing the function of
the parasympathetic and
sympathetic nervous
systems (Chapter 5,
section 5.1), and
describing the nature of
nerve impulses (Chapter 5,
section 5.2 ).