[63] Tu X., Ling F., Huang A., Zhang Q., Wang G. Anthelmintic efficacy of Santalum album
(Santalaceae) against monogenean infections in goldfish. Parasitology Research. 2013; 112 :
2839 ‐2845. doi:10.1007/s00436‐013‐3455‐7.
[64] Wink M. Evolutionary advantage and molecular modes of action of multi‐compo‐
nent mixtures used in phytomedicine. Current Drug Metabolism. 2008;9:996‐1009.
doi:10.2174/138920008786927794.
[65] Xu X., Zhang Y., Qu D., Jiang T., Li S. Osthole induces G2/M arrest and apoptosis in lung
cancer A549 cells by modulating PI3K/Akt pathway. Journal of Experimental & Clinical
Cancer Research. 2011;30:33‐39. doi:10.1186/1756‐9966‐30‐33
[66] Zhang L., Jiang G., Yao F., He Y., Liang G., Zhang Y., Hu B., Wu Y., Li Y., Liu H. Growth
inhibition and apoptosis induced by osthole, a natural coumarin, in hepatocellular car‐
cinoma. PLoS One. 2012; 7 :1‐9. doi:10.1371/journal.pone.0037865.
[67] Ogawa H., Sasai N., Kamisako T., Baba K. Effects of osthol on blood pressure and lipid metab‐
olism in stroke‐prone spontaneously hypertensive rats. Journal of Ethnopharmacology.
2007; 112 :26‐31. doi:10.1016/j.jep.2007.01.028.
[68] Hsieh M.T., Hsieh C.L., Wang W.H., Chen C.S., Lin C.J., Wu C.R. Osthole improves
aspects of spatial performance in ovariectomized rats. The American Journal of Chinese
Medicine. 2004; 32 :11‐20. doi:10.1142/S0192415X04001758.
[69] Liao L. ‐L., Kupchan M., Horwitz S.B. Mode of action of the antitumor compound
bruceantin, an inhibitior of protein synthesis. Molecular Pharmacology. 1976; 12 :167‐176.
[70] Kirby G.C., O'Neill M.J., Phillipson J.D., Warhurst D.C. In vitro studies on the mode of
action of quassinoids with activity against chloroquine‐resistant Plasmodium falciparum.
Biochemical Pharmacology. 1989; 8 :4367‐4374. doi:10.1016/0006‐2952(89)90644‐8.
[71] Fukamya N., Lee K.‐H., Muhammad I., Murakami C., Okano M., Harvey I., Pelletier J.
Structure‐activity relationships of quassinoids for eukaryotic protein synthesis. Cancer
Letters. 2005; 220 :37‐48. doi:10.1016/j.canlet.2004.04.023.
[72] Guo Z., Vangapandu S., Sindelar R.W., Walker L.A., Sindelar R.D. Biologically active
quassinoids and their chemistry: potential leads for drug design.Current Medicinal
Chemistry. 2005; 12 :173‐190. doi:10.2174/0929867053363351.
[73] Kemény‐Beke A., Aradi J., Damjanovich J., Beck Z., Facskó A., Berta A., Bodnár A.
Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguin‐
arine and chelerythrine. Cancer Letters. 2006; 237 :67‐75. doi:10.1016/j.canlet.2005.05.037.
[74] Umeda N., Nibe H., Hara T., Hirazawa N. Effects of various treatments on hatch‐
ing of eggs and viability of oncomiracidia of the monogenean Pseudodactylogyrus
anguillae and Pseudodactylogyrus bini. Aquaculture. 2006; 253 :148‐153. doi:10.1016/j.
aquaculture.2005.08.009.
[75] Cabello F.C. Heavy use of prophylactic antibiotics in aquaculture: a growing problem
for human and animal health and for the environment. Environmental Microbiology.
2006; 8 :1137‐1144. doi:10.1111/j.1462‐2920.2006.01054.x.
134 Natural Remedies in the Fight Against Parasites