Stem Cell Microenvironments and Beyond

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Colmone A, Amorim M, Pontier AL, Wang S, Jablonski E, Sipkins DA (2008) Leukemic cells
create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells.
Science 322:1861–1865
Ding L, Saunders TL, Enikolopov G, Morrison SJ (2012) Endothelial and perivascular cells main-
tain haematopoietic stem cells. Nature 481:457–462
Doan PL, Chute JP (2012) The vascular niche: home for normal and malignant hematopoietic stem
cells. Leukemia 26:54–62
Dores GM, Devesa SS, Curtis RE, Linet MS, Morton LM (2012) Acute leukemia incidence and
patient survival among children and adults in the United States, 2001-2007. Blood 119:34–43
Drolle H, Wagner M, Vasold J, Kütt A, Deniffel C, Sotlar K et al (2015) Hypoxia regulates prolif-
eration of acute myeloid leukemia and sensitivity against chemotherapy. Leuk Res 39:779–785
Dührsen U, Hossfeld DK (1996) Stromal abnormalities in neoplastic bone marrow diseases. Ann
Hematol 73:53–70
Ferrara N, Gerber HP, LeCouter J  (2003) The biology of VEGF and its receptors. Nat Med
9:669–676
Fiegl M, Samudio I, Clise-Dwyer K, Burks JK, Mnjoyan Z, Andreeff M (2009) CXCR4 expres-
sion and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure.
Blood 113:1504–1512
Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R et al (2011) In vivo imaging of Treg
cells providing immune privilege to the haematopoietic stem-cell niche. Nature 474:216–219
Griessinger E, Anjos-Afonso F, Pizzitola I, Rouault-Pierre K, Vargaftig J, Taussig D et al (2014) A
niche-like culture system allowing the maintenance of primary human acute myeloid leukemia-
initiating cells: a new tool to decipher their chemoresistance and self-renewal mechanisms.
Stem Cells Transl Med 3:520–529
Hanahan D, Coussens LM (2012) Accessories to the crime: functions of cells recruited to the
tumor microenvironment. Cancer Cell 21:309–322
Hanoun M, Zhang D, Mizoguchi T, Pinho S, Pierce H, Kunisaki Y et al (2014) Acute myelogenous
leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic
stem cell niche. Cell Stem Cell 15:365–375
Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ et  al (2013) Niche-
based screening identifies small-molecule inhibitors of leukemia stem cells. Nat Chem Biol
9:840–848
Herrlich P, Morrison H, Sleeman J, Orian-Rousseau V, König H, Weg-Remers S et al (2000) CD44
acts both as a growth- and invasiveness-promoting molecule and as a tumor-suppressing cofac-
tor. Ann N Y Acad Sci 910:106–118. discussion 18-20
Hsieh YT, Gang EJ, Geng H, Park E, Huantes S, Chudziak D et al (2013) Integrin alpha4 block-
ade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy. Blood
121:1814–1818
Hussong JW, Rodgers GM, Shami PJ (2000) Evidence of increased angiogenesis in patients with
acute myeloid leukemia. Blood 95:309–313
Ito K, Carracedo A, Weiss D, Arai F, Ala U, Avigan DE et al (2012) A PML–PPAR-δ pathway for
fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat Med 18:1350–1358
Jacamo R, Chen Y, Wang Z, Ma W, Zhang M, Spaeth EL et  al (2014) Reciprocal leukemia-
stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance. Blood
123:2691–2702
Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE (2006) Targeting of CD44 eradicates human
acute myeloid leukemic stem cells. Nat Med 12:1167–1174
Katayama Y, Battista M, Kao WM, Hidalgo A, Peired AJ, Thomas SA et al (2006) Signals from
the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow.
Cell 124:407–421
Kfoury Y, Mercier F, Scadden DT (2014) SnapShot: The hematopoietic stem cell niche. Cell
158:228–2e1


3 Leukemia Stem Cells Microenvironment

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