255
Li QY, Uygun BE, Geerts S, Ozer S, Scalf M, Gilpin SE, Ott HC, Yarmush ML, Smith LM,
Welham NV, Frey BL (2016) Proteomic analysis of naturally-sourced biological scaffolds.
Biomaterials 75:37–46. doi:10.1016/j.biomaterials.2015.10.011
Litingtung Y, Lei L, Westphal H, Chiang C (1998) Sonic hedgehog is essential to foregut develop-
ment. Nat Genet 20(1):58–61
Longmire TA, Ikonomou L, Hawkins F, Christodoulou C, Cao YX, Jean JC, Kwok LW, Mou HM,
Rajagopal J, Shen SS, Dowton AA, Serra M, Weiss DJ, Green MD, Snoeck HW, Ramirez MI,
Kotton DN (2012) Efficient derivation of purified lung and thyroid progenitors from embryonic
stem cells. Cell Stem Cell 10(4):398–411. doi:10.1016/j.stem.2012.01.019
McQualter JL, Yuen K, Williams B, Bertoncello I (2010) Evidence of an epithelial stem/progenitor
cell hierarchy in the adult mouse lung. Proc Natl Acad Sci USA 107(4):1414–1419. doi:10.1073/
pnas.0909207107
Metzger RJ, Klein OD, Martin GR, Krasnow MA (2008) The branching programme of mouse lung
development. Nature 453(7196):745–7U1. doi:10.1038/nature07005
Minoo P, Su GS, Drum H, Bringas P, Kimura S (1999) Defects in tracheoesophageal and lung
morphogenesis in Nkx2.1(−/−) mouse embryos. Dev Biol 209(1):60–71
Morrisey EE, Hogan BLM (2010) Preparing for the first breath: genetic and cellular mechanisms
in lung development. Dev Cell 18(1):8–23. doi:10.1016/j.devcel.2009.12.010
Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui CC (1998) Essential function of Gli2 and Gli3 in
the formation of lung, trachea and oesophagus. Nat Genet 20(1):54–57
Mou HM, Zhao R, Sherwood R, Ahfeldt T, Lapey A, Wain J, Sicilian L, Izvolsky K, Musunuru K,
Cowan C, Rajagopal J (2012) Generation of multipotent lung and airway progenitors from
mouse ESCs and patient-specific cystic fibrosis iPSCs. Cell Stem Cell 10(4):385–397.
doi:10.1016/j.stem.2012.01.018
Naba A, Clauser KR, Hoersch S, Liu H, Carr SA, Hynes RO (2012) The matrisome: in silico defi-
nition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Mol Cell Proteomics 11(4):18. doi:10.1074/mcp.M111.014647
Ott HC, Matthiesen TS, Goh SK, Black LD, Kren SM, Netoff TI, Taylor DA (2008) Perfusion-
decellularized matrix: using nature’s platform to engineer a bioartificial heart. Nat Med
14(2):213–221. doi:10.1038/nm1684
Ott HC, Clippinger B, Conrad C, Schuetz C, Pomerantseva I, Ikonomou L, Kotton D, Vacanti JP
(2010) Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med 16(8):927–
U131. doi:10.1038/nm.2193
Pepicelli CV, Lewis PM, McMahon AP (1998) Sonic hedgehog regulates branching morphogen-
esis in the mammalian lung. Curr Biol 8(19):1083–1086
Petersen TH, Calle EA, Zhao LP, Lee EJ, Gui LQ, Raredon MB, Gavrilov K, Yi T, Zhuang ZW,
Breuer C, Herzog E, Niklason LE (2010) Tissue-engineered lungs for in vivo implantation.
Science 329(5991):538–541. doi:10.1126/science.1189345
Price AP, England KA, Matson AM, Blazar BR, Panoskaltsis-Mortari A (2010) Development of a
decellularized lung bioreactor system for bioengineering the lung: the matrix reloaded. Tissue
Eng Part A 16(8):2581–2591. doi:10.1089/ten.tea.2009.0659
Randell SH, Comment CE, Ramaekers FCS, Nettesheim P (1991) Properties of rat tracheal
epithelial- cells separated based on expression of cell-surface alpha-galactosyl end groups. Am
J Respir Cell Mol Biol 4(6):544–554
Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM,
Shannon JM, Zorn AM (2016) A retinoic acid-hedgehog cascade coordinates mesoderm- inducing
signals and endoderm competence during lung specification. Cell Rep 16(1):66–78.
doi:10.1016/j.celrep.2016.05.060
Ren X, Moser PT, Gilpin SE, Okamoto T, Wu T, Tapias LF, Mercier FE, Xiong LJ, Ghawi R,
Scadden DT, Mathisen DJ, Ott HC (2015) Engineering pulmonary vasculature in decellular-
ized rat and human lungs. Nat Biotechnol 33(10):1097. doi:10.1038/nbt.3354
13 Development and Bioengineering of Lung Regeneration