Organ Regeneration Based on Developmental Biology

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Contents

1 Telencephalic Tissue Formation in 3D Stem Cell Culture .................. 1
Taisuke Kadoshima, Hideya Sakaguchi, and Mototsugu Eiraku

2 Self-Organized Cerebellar Tissue from Human Pluripotent
Stem Cells and Its Application to Clinical Medicine ........................... 25
Keiko Muguruma

3 Functional Pituitary Tissue Formation Recapitulating
Hypothalamus and Pituitary Development Using ES/iPS Cells ......... 41
Hidetaka Suga and Chikafumi Ozone

4 Inner Ear Organoids: Recapitulating Inner
Ear Development in 3D Culture ............................................................ 57
Alhasan N. Elghouche, Rick F. Nelson, and Eri Hashino

5 Functional Tooth Regeneration ............................................................. 73
Masamitsu Oshima and Takashi Tsuji

6 Functional Hair Follicle Regeneration .................................................. 97
Koh-ei Toyoshima and Takashi Tsuji

7 Functional Salivary Gland Regeneration ............................................. 121
Miho Ogawa and Takashi Tsuji

8 Functional Lacrimal Gland Regeneration ............................................ 135
Masatoshi Hirayama, Kazuo Tsubota, and Takashi Tsuji

9 Early Kidney Specification and Its Recapitulation
by Pluripotent Stem Cells ....................................................................... 153
Atsuhiro Taguchi and Ryuichi Nishinakamura

10 Generation of Gastrointestinal Organoids Derived
from Human Pluripotent Stem Cells ..................................................... 179
Jorge O. Múnera and James M. Wells