Imaging in Stem Cell Transplant and Cell-based Therapy

124

Table 8.1

(continued)

Study

Setting

Route of delivery

LVEF/technique used

Myocardial perfusion/technique used

Infarct size/technique used

Myocardial viability/technique used

Strauer et al.

AMI

Intracoronary

No change/LV angiography

Decreased perfusion defect/TI-SPECT

Decreased/LV angiography

No change in contractile reserve/DSE

Katritsis et al.

CMI

Intracoronary

No change/echo

Decreased perfusion defect/Tc-SPECT

Decreased/Tc SPECT

Increased viability/DSE

AMI

acute myocardial infarction,

CMI

chronic myocardial infarction,

AP

angina pectoris,

HF

heart failure,

LV

left ventricular,

NA

not available,

MRI

magnetic

resonance imaging,

DSE

dobutamine stress echocardiography,

F18-FDG

F18-fluorodeoxyglucose,

PET

positron emission tomography,

Tc

technetium,

Tl

thal

• 
  

lium,

SPECT

single-photon emission computed tomography; Studies:

TOPCARE-AMI

transplantation of progenitor cells and regeneration enhancement in

acute myocardial infarction,

ASTAMI

evaluation of treatment with intracoronary mononuclear autologous bone marrow cell therapy among patients with acute

anterior myocardial infarction treated with primary percutaneous coronary intervention,

BOOST

bone marrow transfer to enhance ST-elevation infarct regen

• 
  

eration,

IACT

regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease,

MAGIC

effects of intracoronary infusion of peripheral blood stem cells mobilized with granulocyte colony-stimulating factor on LV systolic function and

restenosis after coronary stenting in MI,

MRI

magnetic resonance imaging,

TOPCARE-CHD

transplantation of progenitor cells and regeneration enhancement

in congenital heart disease

S. Raina et al.