Caspases,Paracaspases, and Metacaspases Methods and Protocols

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  1. Stennicke HR, Salvesen GS (1999) Catalytic
    properties of the caspases. Cell Death Differ
    6:1054–1059

  2. Pop C, Fitzgerald P, Green DR, Salvesen GS
    (2007) Role of proteolysis in caspase-8 activa-
    tion and stabilization. Biochemistry
    46:4398–4407

  3. Zhou Q, Salvesen GS (1997) Activation of pro-
    caspase-7 by serine proteases includes a non-
    canonical specificity. Biochem J 324:361–364

  4. Stennicke HR et al (1998) Pro-caspase-3 is a
    major physiologic target of caspase-8. J Biol
    Chem 273:27084–27090

  5. Chao Y et al (2005) Engineering a dimeric
    caspase- 9: a re-evaluation of the induced prox-
    imity model for caspase activation. PLoS Biol
    3:e183

  6. Walters J et al (2009) A constitutively active
    and uninhibitable caspase-3 zymogen efficiently
    induces apoptosis. Biochem J 424:335–345

  7. Swan ID (1972) The inhibition of hen egg-
    white lysozyme by imidazole and indole deriva-
    tives. J Mol Biol 65:59–62

  8. Bury A (1981) Analysis of protein and peptide
    mixtures: evaluation of three sodium dodecyl
    sulphate-polyacrylamide gel electrophoresis
    buffer systems. J Chromatogr 213:491–500

  9. Edelhoch H (1967) Spectroscopic determina-
    tion of tryptophan and tyrosine in proteins.
    Biochemistry 6:1948–1954

  10. Zhou Q, Salvesen GS (2000) Viral caspase
    inhibitors CrmA and p35. Methods Enzymol
    322:143–154

  11. Zhou Q et al (1998) Interaction of the bacu-
    lovirus anti-apoptotic protein p35 with cas-
    pases: specificity, kinetics, and characterization
    of the caspase/p35 complex. Biochemistry
    37:10757–10765
    51. Oberst A et al (2011) Catalytic activity of the
    caspase-8-FLIP(L) complex inhibits RIPK3-
    dependent necrosis. Nature 471:363–367
    52. Oberst A et al (2010) Inducible dimerization
    and inducible cleavage reveal a requirement for
    both processes in caspase-8 activation. J Biol
    Chem 285:16632–16642
    53. van Raam BJ, Ehrnhoefer DE, Hayden MR,
    Salvesen GS (2013) Intrinsic cleavage of
    receptor- interacting protein kinase-1 by cas-
    pase- 6. Cell Death Differ 20:86–96
    54. Gray DC, Mahrus S, Wells JA (2010) Activation
    of specific apoptotic caspases with an engi-
    neered small-molecule-activated protease. Cell
    142:637–646
    55. Witkowski WA, Hardy JA (2009) L2′ loop is
    critical for caspase-7 active site formation.
    Protein Sci 18:1459–1468
    56. Witkowski WA, Hardy JA (2011) A designed
    redox-controlled caspase. Proc Natl Acad Sci U
    S A 20(8):1421–1431
    57. Hardy JA, Lam J, Nguyen JT, O’Brien T, Wells JA
    (2004) Discovery of an allosteric site in the caspases.
    Proc Natl Acad Sci U S A 101:12461–12466
    58. Scheer JM, Romanowski MJ, Wells JA (2006) A
    common allosteric site and mechanism in caspases.
    Proc Natl Acad Sci U S A 103:7595–7600
    59. Velazquez-Delgado EM, Hardy JA (2012)
    Zinc-mediated allosteric inhibition of caspase-
    6. J Biol Chem 287:36000–36011
    60. Denault JB, Eckelman BP, Shin H, Pop C, Salvesen
    GS (2007) Caspase 3 attenuates XIAP (X-linked
    inhibitor of apoptosis protein)-mediated inhibition
    of caspase 9. Biochem J 405:11–19
    61. Boucher D, Blais V, Denault JB (2012)
    Caspase-7 uses an exosite to promote poly(ADP
    ribose) polymerase 1 proteolysis. Proc Natl
    Acad Sci U S A 109(15):5669–5674


Apoptotic Caspases Assays
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