Revival: Biological Effects of Low Level Exposures to Chemical and Radiation (1992)

100 BIOLOGICAL EFFECTS OF LOW LEVEL EXPOSURES

Table 5.3. Number of Thoracic Duct Lymphocytes as a Function of Radiation Dose and Time After IrradiationRadiation

4 Hours

10 Hours

21 Hours

46 Hours

Dose

No. of No. of

Percent Percent No. of

Percent Percent No. of

Percent Percent No. of

Percent Percent

(rads)

Mice Cells Viability

T

B

Cells Viability

T

B

Cells Viability

T

B

Cells Viability

T

B

0 4 11.8 100 65 33 25.6 98

58 39 33.5 99 56 43 33.8 99

54 48

50 4 9.8 99 63 35 14.5 99 56 44 18.7 99 52

48 7.4 99

53 48

100 8 6.8 99 89 11 8.8 99

90

9 6.1 95 85

11 6.1 95

86 14

300 4 9.5 99 87

9 3.7 96

93

7 6.4 99 93

9 4.6 99

92

6

500 5 3.8 99 59 35 4.8 100 58 40 3.3 100 52 47 1.2 99

55 41

Source:

After Anderson and Williams.17

Note:

Four-month-old CBA female mice were exposed in whole-body fashion to indicated dose. Immediately after irradiation the thoracic duct was cannulated, and the number of TDL determined at the indicated times. Only mice which flowed well were employed for data calculations. Results represent cumulative cell numbers.