Revival: Biological Effects of Low Level Exposures to Chemical and Radiation (1992)

Contents

1. Hypotheses on Mammalian Aging, Toxicity, and Longevity
   Hormesis: Explication by a Generalized Gompertz Function,
   Harold Boxenbaum........................................................................ 1


2. The Role of the “Stress Protein Response” in Hormesis,
   Joan Smith-Sonneborn.................................................................. 41


3. DNA Repair: As Influenced by Age, Nutrition, and Exposure
   to Toxic Substances, Ronald Hart, Ming Chou, Ritchie
   Feuers, Julian Leakey, Peter Duffy, Beverly Lyn-Cook, Jack
   Lipman, Kenji Nakamura, Angelo Turturro,
   and William Allaben...................................................................... 53


4. Biochemical Mechanisms of Biphasic Dose-Response
   Relationships: Role of Hormesis, Harihara M. Mehendale .... 59


5. Effects of Low-Dose Radiation on the Immune Response,
   Robert E. Anderson...................................................................... 95


6. Cellular Adaptation as an Important Response During
   Chemical Carcinogenesis, Emmanuel Farber............................. 113


7. Biostatistical Approaches for Modeling U-Shaped
   Dose-Response Curves and Study Design Considerations in
   Assessing the Biological Effects of Low Doses, Tom Downs... 119

List of Contributors.................................................................................... 147

Index 149