References
Abell CW, Kwan SW. Molecular characterization of monoamine oxidases A and B.
Prog Nucleic Acid Res Mol Biol 2001;65:129–156.
Bauman JN, Goosen TC, Tugnait M, Peterkin V, Hurst SI, Menning LC, Milad M,
Court MH, Williams JA. UDP-Glucuronosyltransferase 2B7 is the major enzyme
responsible for gemcabene glucuronidation in human liver microsomes. Drug Metab
Dispos 2005;33:1349–1354.
Bjornsson TD, Callaghan JT, Einolf HJ, Fischer V, Gan L, Grimm S, Kao J, King SP,
Miwa G, Ni L, Kumar G, McLeod J, Obach RS, Roberts S, Roe A, Shah A, Snikeris
F, Sullivan JT, Tweedie D, Vega JM, Walsh J, Wrighton SA. The conduct ofin vitro
andin vivodrug–drug interaction studies: a pharmaceutical research and manufac-
turers of America (PhRMA) perspective. Drug Metab Dispos 2003;31:815–832.
Bu HZ, Kang P, Zhao P, Pool WF, Wu EY. A simple sequential incubation method for
deconvoluting the complicated sequential metabolism of capravirine in humans.
Drug meta dispos: the biological fate of chemicals 2005;33:1438–1445.
Bu HZ, Zhao P, Kang P, Pool WF, Wu EY. Identification of enzymes responsible for
primary and sequential oxygenation reactions of capravirine in human liver
microsomes. Drug metab dispos: the biological fate of chemicals 2006;34:1798–1802.
Busby WF, Jr, Ackermann JM, Crespi CL. Effect of methanol, ethanol, dimethyl
sulfoxide, and acetonitrile on in vitro activities of cDNA-expressed human
cytochromes P-450. Drug Metab Dispos 1999;27:246–249.
Cashman JR. Structural and catalytic properties of the mammalian flavin-containing
monooxygenase. Chem Res Toxicol 1995;8:166–181.
Cashman JR. Human flavin-containing monooxygenase (form 3): polymorphisms and
variations in chemical metabolism. Pharmacogenomics 2002;3:325–339.
Cashman JR. The role of flavin-containing monooxygenases in drug metabolism and
development. Curr Opin Drug Discov Devel 2003;6:486–493.
Cashman JR. The implications of polymorphisms in mammalian flavin-containing
monooxygenases in drug discovery and development. Drug Discov Today
2004;9:574–581.
Cashman JR, Zhang J. Interindividual differences of human flavin-containing
monooxygenase 3: genetic polymorphisms and functional variation. Drug Metabol
Dispos 2002;30:1043–1052.
Chauret N, Gauthier A, Nicoll-Griffith DA. Effect of common organic solvents onin
vitrocytochrome P450-mediated metabolic activities in human liver microsomes.
Drug Metab Dispos 1998;26:1–4.
Crespi CL, Langenbach R, Penman BW. Human cell lines, derived from AHH-1
TK+/human lymphoblasts, genetically engineered for expression of cytochromes
P450. Toxicology 1993;82:89–104.
Crespi CL, Miller VP. The use of heterologously expressed drug metabolizing
enzymes––state of the art and prospects for the future. Pharmacol Ther
1999;84:121–131.
Cygler M, Schrag JD, Sussman JL, Harel M, Silman I, Gentry MK, Doctor BP.
Relationship between sequence conservation and three-dimensional structure in a
large family of esterases, lipases, and related proteins. Protein Sci 1993;2:366–382.
REFERENCES 505