Egger, D., Wehtje, E., Adlercreutz, P. (1997), Characterization and optimization of phospholipase A 2
catalyzed synthesis of phosphatidylcholine,Biochim. Biophys. Acta 1343 , 76–84.
Haas, M.J., Cichowicz, D.J., Phillips, J., Moreau, R. (1993), The hydrolysis of phosphatidylcholine by an
immobilized lipase: optimization of hydrolysis in organic solvents,J. Am. Oil Chem. Soc. 70 ,111–117.
Han, J.J., Rhee, J.S. (1995), Lipase-catalyzed synthesis of lysophosphatidic acid in a solvent free system,
Biotechnol. Lett. 17 , 531–536.
Han, J.J., Rhee, J.S. (1998), Effect of salt hydrate pairs for water activity control on lipase-catalyzed
synthesis of lysophospholipids in a solvent-free system,Enzyme Microb. Techn. 22 , 158–164.
Hara, F., Nakashima, T., Fukuda, H. (1997), Comparative study of commercially available lipases in
hydrolysis reaction of phosphatidylcholine,J. Am. Oil Chem. Soc. 74 , 1129–1132.
Ha ̈rro ̈d, M., Elfman, I. (1995), Enzymatic synthesis of phosphatidylcholine with fatty acids, isooctane,
carbon dioxide, and propane as solvents,J. Am. Oil Chem. Soc. 72 , 641–646.
Hosokawa, M., Ito, M., Takahashi, K. (1998), Preparation of highly unsaturated fatty acid-containing
phosphatidylcholine by transesterification with phospholipase A 2 ,Biotechnol. Technol. 12 , 583–586.
Hosokawa, M., Takahashi, K., Hatano, M., Egi, M. (1995a), Phospholipase A 2 -mediated synthesis of
phosphatidylethanolamine containing highly unsaturated fatty acids,Int. J. Food Sci. Technol. 29 ,
721–725.
Hosokawa, M., Takahashi, K., Miyazaki, N., Okamura, K., Hatano, M. (1995b), Application of water
mimics on preparation of eicosapentaenoic and docosahexaenoic acids containing glycerolipids,J.
Am. Oil Chem. Soc. 72 , 421–425.
Inada, Y. (1996), Manufacture of glycerophosphorylcholine from phosphatidylcholine with modified
lipase,Japanese patent,JP 63105685 A2 880510.
Lilja-Hallberg, M., Ha ̈rro ̈d, M. (1995), Enzymatic and non-enzymatic esterification of long polyunsatu-
rated fatty acids and lysophosphatidylcholine in isooctane,Biocatal. Biotransform. 12 , 55–66.
Mazur, A.W., Hiler, G.D.I., Lee, S.S.C., Armstrong, M.P., Wendel, J.D. (1991), Regio- and stereoselective
enzymatic esterification of glycerol and its derivatives,Chem. Phys. Lipids 60 , 189–199.
Millqvist Fureby, A., Virto, C., Adlercreutz, P., Mattiasson, B. (1996), Acyl groups migrations in 2-mono-
olein,Biocatal. Biotransform. 14 , 89 – 111.
Mingarro, I., Abad, C., Braco, L. (1994), Characterization of acylating and deacylating activities of an
extracellular phospholipase A 2 in a water-restricted environment,Biochemistry 33 , 4652–4660.
Morgado, M.A.P., Cabral, J.M.S., Prazeres, D.M.F. (1995), Hydrolysis of lecithin by phospholipase A 2 in
mixed reversed micelles of lecithin and sodium dioctyl sulfosuccinate,J. Chem. Tech. Biotechnol. 63 ,
181–189.
Morimoto, T., Muramaki, N., Nagatsu, A., Sakakibara, J. (1993), Regiospecific deacylation of glycer-
ophospholipids by use ofMucor javanicuslipase,Tetrahedron Lett. 34 , 2487–2490.
Na, A., Eriksson, C., O ̈sterberg, E., Holmberg, K. (1990), Synthesis of phosphatidylcholine with (n-3)
fatty acids by phospholipase A 2 in microemulsion,J. Am. Oil Chem. Soc. 67 , 766–770.
Paltauf, F., Hermetter, A. (1994), Strategies for the synthesis of glycerophospholipids,Prog. Lipid Res. 33 ,
239–328.
Pernas, P., Olivier, J.L., Legoy, M.D., Bereziat, G. (1990), Phospholipid synthesis by extracellular phos-
pholipase A 2 in organic solvents,Biochem. Biophys. Res. Commun. 168 , 644–650.
Sarney, D.B., Fregapane, G., Vulfson, E.N. (1994), Lipase-catalyzed synthesis of lysophospholipids in a
continuous bioreactor,J. Am Oil Chem. Soc. 71 , 93–96.
Servi, S. (1999), Phospholipases as synthetic catalysts,Top. Curr. Chem. 200 , 127–158.
Svensson, I., Adlercreutz, P., Mattiasson, B. (1992), Lipase-catalyzed transesterification of phosphatidyl-
choline at controlled water activity,J. Am. Oil Chem. Soc. 69 , 986–991.
Valivety, R.H., Halling, P.J., Macrae, A.R. (1992),Rhizomucor mieheilipase remains highly active at
water activity below 0.0001,FEBS Lett. 301 , 258–260.
Virto, C., Adlercreutz, P. (2000a), Lysophosphatidylcholine synthesis withCandida antarcticalipase B
(Novozyme 435),Enzyme Microb. Technol. 26 , 630–635.
Virto, C., Adlercreutz, P. (2000b), Two-enzyme system for the synthesis of 1–lauroyl-glycerophosphate
(lysophosphatidic acid) and 1-lauroyl-dihydroxyacetonephosphate,Chem. Phys. Lipids, 109 , 175–
184.
Virto, C., Svensson, I., Adlercreutz, P. (1999), Enzymatic synthesis of lysophosphatidic acid and phos-
phatidic acid,Enzyme Microb. Technol. 24 , 651–658.
tina sui
(Tina Sui)
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