527
Interactions
Integumentary System
- The skin serves as first line of
defense against invasion by
pathogens (p. 494) - Dendritic cells in the epidermis and
macrophages in the dermis present
antigens that trigger the immune
response (p. 510) - Mast cells contribute to
inflammation (p. 500)
Skeletal System
- Hematopoiesis, including formation
of leukocytes involved in immunity,
occurs in the bone marrow (p. 409) - The immune system protects all
systems, including the skeletal
system, against infection (p. 494)
Muscular System
- Cardiac muscle in the heart pumps
blood to the body organs, including
those of the immune system
(p. 418) - The smooth muscle of blood
vessels helps regulate blood flow to
areas of infection (p. 501)
Nervous System
- Neural regulation of the pituitary
and adrenal glands indirectly
influences activity of the immune
system (p. 514) - Nerves regulate blood flow to most
organs, including the lymphatic
organs (p. 466)
Endocrine System
- The pituitary and adrenal glands
influence immune function (p. 340) - The thymus regulates the production
of T lymphocytes (p. 499)
Circulatory System
- The circulatory system transports
neutrophils, monocytes, and
lymphocytes to infected areas
(p. 405) - Hematopoiesis generates the cells
required for the immune response
(p. 409)
Respiratory System
- The lungs provide oxygen for
transport by the blood and
eliminate carbon dioxide from the
blood (p. 533)
Urinary System
- The kidneys regulate the volume,
pH, and electrolyte balance of the
blood and eliminate wastes (p. 582) - The immune system protects
against infection of the urinary
system (p. 494)
Digestive System
- The GI tract provides nutrients for
all body cells, including those of the
immune system (p. 620) - Stomach acid serves as a barrier to
pathogens (p. 494)- Areas of the GI tract contain
numerous lymphocytes and
lymphatic nodules (p. 634)
- Areas of the GI tract contain
Reproductive System
- The blood-testes barrier prevents
sperm cell antigens from provoking
an autoimmune response (p. 716) - Vaginal acidity inhibits the spread
of pathogens (p. 494) - The placenta is an immunologically
privileged site that is normally
protected from immune attack (p. 741) - A mother’s breast milk provides
antibodies that passively immunize
her baby (p. 748)
HPer Links of the Immune System with Other Body Systems