- Kurumbail RG, Calabrese MF (2016) Struc-
ture and regulation of AMPK. EXS 107:3–22.
https://doi.org/10.1007/978-3-319-43589-
3_1
- Langendorf CG, Kemp BE (2015) Choreogra-
phy of AMPK activation. Cell Res 25(1):5–6.
https://doi.org/10.1038/cr.2014.163
- Langendorf CG, Ngoei KR, Scott JW, Ling
NX, Issa SM, Gorman MA, Parker MW,
Sakamoto K, Oakhill JS, Kemp BE (2016)
Structural basis of allosteric and synergistic
activation of AMPK by furan-2-phosphonic
derivative C2 binding. Nat Commun
7:10912. https://doi.org/10.1038/
ncomms10912
- Calabrese MF, Rajamohan F, Harris MS, Cas-
pers NL, Magyar R, Withka JM, Wang H, Bor-
zilleri KA, Sahasrabudhe PV, Hoth LR,
Geoghegan KF, Han S, Brown J, Subashi TA,
Reyes AR, Frisbie RK, Ward J, Miller RA,
Landro JA, Londregan AT, Carpino PA,
Cabral S, Smith AC, Conn EL, Cameron KO,
Qiu X, Kurumbail RG (2014) Structural basis
for AMPK activation: natural and synthetic
ligands regulate kinase activity from opposite
poles by different molecular mechanisms.
Structure 22(8):1161–1172.https://doi.org/
10.1016/j.str.2014.06.009
- Hunter RW, Foretz M, Bultot L, Fullerton
MD, Deak M, Ross FA, Hawley SA,
Shpiro N, Viollet B, Barron D, Kemp BE,
Steinberg GR, Hardie DG, Sakamoto K
(2014) Mechanism of action of compound-
13: an alpha1-selective small molecule activator
of AMPK. Chem Biol 21(7):866–879.https://
doi.org/10.1016/j.chembiol.2014.05.014
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