Hypothalamus
Selective estrogen
receptor modulators
Estradiol
GnRH
GnIH
Aromatase
inhibitors
Aromatase
Te stosterone
(serum~500 ng/dl)
Te stosterone
(~500 ng/dl)
Leydig cells
Sertoli cells
FSH Inhibion B
Activin
LH
Testes
Anterior pituitary
Figure 7.16 Hypothalamic–pituitary–gonadal network. Source: Adapted from http://www.
maleinfertility.org/sites/default/files/styles/panopoly_image_original/public/new_hpg.
jpg?itok=J3X4BcOu and Pinterest: hypothalamic‐pituitary‐adrenal.