Chapter 16 Biological Therapies in Canine Sports Medicine 421Black, L. L., Gaynor, J., Gahring, D., Adams, C.,
Aron, D., Harman, S., et al. 2007. Effect of adipose‐
derived mesenchymal stem and regenerative cells
on lameness in dogs with chronic osteoarthritis
of the coxofemoral joints: a randomized, double‐
blinded, multicenter, controlled trial. Vet Ther, 8(4),
272–284.
Black, L. L., Gaynor, J., Adams, C., Dhupa, S., Sams,
A. E., Taylor, R., et al. 2008. Effect of intraarticular
injection of autologous adipose‐derived mesen‑
chymal stem and regenerative cells on clinical
signs of chronic osteoarthritis of the elbow joint in
dogs. Vet Ther, 9(3), 192–200.
Bozynski, C. C., Stannard, J. P., Smith, P., Hanypsiak,
B. T., Kuroki, K., Stoker, A., et al. 2016. Acute man‑
agement of anterior cruciate ligament injuries
using novel canine models. J Knee Surg, 29(7),
594–603.
Braun, H. J., Kim, H. J., Chu, C. R. & Dragoo, J. L.
- The effect of platelet‐rich plasma formula‑
tions and blood products on human synoviocytes:
implications for intra‐articular injury and therapy.
Am J Sports Med, 42(5), 1204–1210.
Canapp, S. O., Jr., Canapp, D. A., Ibrahim, V., Carr, B.
J., Cox, C. & Barrett, J. G. 2016a. The use of adi‑
pose‐derived progenitor cells and platelet‐rich
plasma combination for the treatment of supraspi‑
natus tendinopathy in 55 dogs: a retrospective
study. Front Vet Sci, 9(3), 61.
Canapp, S. O., Jr., Leasure, C. S., Cox, C., Ibrahim, V.
& Carr, B. J. 2016b. Partial cranial cruciate ligament
tears treated with stem cell and platelet‐rich plasma
combination therapy in 36 dogs: a retrospective
study. Front Vet Sci, 14(3), 112.
Carr, B. J., Canapp, S. O., Jr., Mason, D. R, Cox, C. &
Hess, T. 2015. Canine platelet‐rich plasma systems:
a prospective analysis. Front Vet Sci, 2, 73.
Chung, H. W., Park, S. A., Lee, J. H., Chung, D. J.,
Yang, W. J, Kang, E. H., et al. 2013. Percutaneous
transplantation of human umbilical cord‐derived
mesenchymal stem cells in a dog suspected to
have fibrocartilaginous embolic myelopathy. J Vet
Sci, 14(4), 495–497.
Conzemius, M. G. & Evans, R. B. 2012. Caregiver
placebo effect for dogs with lameness from osteo‑
arthritis. J Am Vet Med Assoc, 241(10), 1314–1319.
Cook, J. L., Smith, P. A., Bozynski, C. C., Kuroki, K.,
Cook, C. R., Stoker, A. M. & Pfeiffer, F. M. 2015.
Multiple injections of leukoreduced platelet rich
plasma reduce pain and functional impairment in
a canine model of ACL and meniscal deficiency.
J Orthop Res, 34(4), 607–615.
Crovace, A., Lacitignola, L., Rossi, G. & Francioso, E. - Histological and immunohistochemical
evaluation of autologous cultured bone marrow
mesenchymal stem cells and bone marrow mono‑
nucleated cells in collagenase‐induced tendinitis
of equine superficial digital flexor tendon. Vet Med
Int, 2010, 250978.
Cuervo, B., Rubio, M., Sopena, J., Dominguez, J. M.,
Vilar, J., Morales, M., et al. 2014. Hip osteoarthritis
in dogs: a randomized study using mesenchymal
stem cells from adipose tissue and plasma rich in
growth factors. Int J Mol Sci, 15(8), 13437–13460.
de Bakker, E., Gielen, I., Saunders, J. H., Polis, I.,
Vermerire, S., Peremans, K., et al. 2013. Primary
and concomitant flexor enthesopathy of the
canine elbow. Vet Comp Orthop Traumatol, 26(6),
425–434.
DeLong, J. M., Russell, R. P. & Mazzocca, A. D. 2012.
Platelet‐rich plasma: the PAW classification sys‑
tem. Arthroscopy, 28(7), 998–1009.
Dohan Ehrenfest, D. M., Andia, I., Zumstein, M. A.,
Zhang, C. Q., Pinto, N. R. & Bielecki, T. 2014.
Classification of platelet concentrates (platelet‐
rich plasma‐PRP, platelet‐rich fibrin‐PRF) for
topical and infiltrative use in orthopedic and
sports medicine: current consensus, clinical
implications and perspectives. Muscles Ligaments
Tendons J, 4(1), 3–9.
Fahie, M. A., Ortolano, G. A., Guercio, V., Schaffer,
J. A., Johnston, G., Au, J., et al. 2013. A randomized
controlled trial of the efficacy of autologous platelet
therapy for the treatment of osteoarthritis in dogs.
J Am Vet Med Assoc, 243(9), 1291–1297.
Franklin, S. P. & Cook, J. L. 2013. Autologous condi‑
tioned plasma versus hyaluronan plus corticos‑
teroid for treatment of chronic elbow osteoarthritis
in dogs. Can Vet J, 54(9), 881–884.
Franklin, S. P., Garner, B. C. & Cook, J. L. 2015.
Characteristics of canine platelet‐rich plasma pre‑
pared with five commercially available systems.
Am J Vet Res, 76(9), 822–827.
Franklin, S. P., Birdwhistell, K. E., Strelchik, A.,
Garner, B. C. & Brainard, B. M. 2017a. Influence of
cellular composition and exogenous activation on
growth factor and cytokine concentrations in
canine platelet‐rich plasmas. Front Vet Sci, 4, 40.
Franklin, S. P., Burke, E. E. & Holmes, S. P. 2017b.
The effect of platelet‐rich plasma on osseous heal‑
ing in dogs undergoing high tibial osteotomy.
PLoS One, 12(5), e0177597.
Frisbie, D. D. 2015. Autologous‐conditioned serum:
evidence for use in the knee. J Knee Surg, 28(1),
63–66.
Frye, C. W., Enders, A., Brooks, M. B., Struble A. M. &
Wakshlag, J. J. 2016. Assessment of canine autolo‑
gous platelet‐rich plasma produced with a com‑
mercial centrifugation and platelet recovery kit. Vet
Comp Orthop Traumatol, 29(1), 14–19.
Fufa, D., Shealy, B., Jacobson, M., Kevy, S. & Murray,
M. M. 2008. Activation of platelet‐rich plasma
using soluble type I collagen. J Oral Maxillofac
Surg, 66(4), 684–690.