460 Canine Sports Medicine and Rehabilitation
include oxidative stress, deposition of beta‐
amyloid plaques (as seen in human patients
with Alzheimer’s disease), DNA fragmentation
or damage, and changes in intracellular signal
ing leading to a loss of neurotrophic factors
(Dimakopoulos & Mayer, 2002). Because dogs
can naturally develop cognitive dysfunction,
and they develop brain beta‐amyloid deposi
tion with cognitive deficits, they are being stud
ied as a possible model for Alzheimer’s disease
research (Bosch et al., 2012; Davis & Head,
2014). Grossly, cortical atrophy and increased
ventricular volume have been noted in the aged
canine brain, along with reduced neurogenesis
in the hippocampus, which is responsible for
learning and memory (Head, 2011).
Metabolic changes
Metabolic changes in the geriatric patient
include decreased metabolic rate and immune
compromise (Goldston, 1995). Maintenance
energy requirements in older dogs decline by
approximately 20% as compared with young
adult dogs. Senior diets are commonly
restricted in calories due to reduced caloric
needs in an attempt to prevent weight gain.
However, they should provide an increased
percentage of highly digestible protein, with a
total composition of at least 25% protein
(Laflamme, 2005). According to Larsen and
Farcas, in 2014 there had been no studies that
indicate that geriatric dogs have any decrease
in digestive efficiency or nutrient absorption as
compared with young adult dogs. While some
functional effects of canine aging, such as
diminished hydrochloric acid production and
bile acid secretion, have been noted, these have
little overall significance, much the same as in
humans. The changes that have been docu
mented in aged dogs in the function of the sali
vary glands, small intestine, liver, and pancreas
likely reflect the general organ degeneration
association with aging (senescence) and may
not be clinically relevant as dogs have signifi
cant digestive functional reserves (Larsen &
Farcas, 2014).
Case Study 18.1 Geriatric patient with obesity and compromised mobility
Signalment: 11‐y.o. M/N Labrador Retriever; 117 lbs.
History: Progressive pelvic limb weakness over sev-
eral years. Difficulty rising and going up stairs (fear of
climbing stairs worsened after slipping on stairs sev-
eral months ago). Diminished endurance on long
walks; swims in local pond when possible. Atopy,
hypothyroid.
Receiving Carprofen™ p.o. o.d., levothyroxine
p.o. b.i.d., glucosamine/chondroitin/ASU p.o. o.d.,
omega‐3 fatty acid p.o. o.d., diphenhydramine p.o.
b.i.d., and chlorpheniramine p.o. b.i.d. Recently began
polysulfated glycosaminoglycan (PSGAG) injections.
Referral radiographs: Left stifle lateral view: signifi-
cant DJD; right stifle lateral view: moderate DJD; VD
pelvis, frog‐leg positioning: irregularity of left femoral
head, narrowing of coxofemoral joint spaces, left
greater than right.
Client’s goals: Slow progression of arthritis, enable
patient to accompany client on walks, and provide
best possible quality of life.
Physical examination: BAR; WNL except: signifi-
cantly overweight—body condition score 7–8/9;
panting throughout exam; lacking appropriate
abdominal muscle tone.
Rehabilitation examination:
Posture: Front end loading, moderate lumbar lor-
dosis, pelvis rotated ventral‐cranial; pelvic limb
conformation very upright, tarsi and stifles lack
appropriate angulation.
Sit: Sits with both pelvic limbs extended cranially.
Gait: Slides rear feet rather than lifting them at walk;
circumducts with external rotation of both hip joints;
minimal flexion of stifles and tarsi.
Neurological exam: WNL except patellar reflexes
diminished (left worse than right); proprioception
greatly delayed for both rear feet, with left worse than
the right, correcting each after approximately 3–5
seconds (repeatable).
Transitions: From sternal to stand: pulls forequarters up
then pushes up with both pelvic limbs while pulling
himself forward; immediately transitions from a sit to
sternal—not staying in sit for more than a few seconds.
Palpation: Triceps muscles very tight bilaterally,
mild resistance (muscular) to full thoracic
limb extension bilaterally, slight resistance to full