Devita, Hellman, and Rosenberg's Cancer

LWBK1006-08 LWW-Govindan-Review December 12, 2011 18:49

CHAPTER 8 PRINCIPLES OF

MEDICAL ONCOLOGY

SUJATHA MURALI•SURESH S. RAMALINGAM

DIRECTIONS Each of the numbered items below is followed by lettered answers. Select the

ONE lettered answer that is BEST in each case unless instructed otherwise.

QUESTIONS

Question 8.1. Historically, the first chemotherapeutic drugs used in the clinical setting

were:

A. Anthracyclines

B. Epidermal growth factor receptor (EGFR) inhibitors

C. Antimetabolites

D. Alkylating agents

Question 8.2. In children with lymphoblastic leukemia, folic acid was observed to:

A. Cause disease proliferation

B. Cause disease regression

C. Have no effect

D. Improve survival

Question 8.3. Antimetabolite chemotherapeutic agents include all of the following,

EXCEPT:

A. Gemcitabine

B. Fluoropyrimidines

C. Mitoxantrone

D. Cytarabine

Question 8.4. In a subset of patients with advanced or metastatic disease, which of the

following has curative potential with primary induction chemotherapy?

A. Germ cell cancer

B. Non-small cell lung cancer

C. Gastric cancer

D. Colorectal cancer

Corresponding Chapter inCancer: Principles & Practice of Oncology,Ninth Edition: 28 (Medical Oncology) and

29 (Assessment of Clinical Response).

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