Devita, Hellman, and Rosenberg's Cancer

LWBK1006-14 LWW-Govindan-Review November 24, 2011 11:28

154 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology Review

Question 14.14. A 28-year-old woman with bilateral ductal cancer presents to the medical

oncologist for assessment and treatment. Her medical history is notable

for intussusception at 6 years of age. On her physical examination, the

medicine resident notices small blue/black hyperpigmented macules on

her lips, buccal mucosa, and fingertips. What is her syndrome diagnosis?

A. Hereditary BRCA1 syndrome

B. Hereditary BRCA2 syndrome

C. Li-Fraumeni syndrome

D. Peutz-Jeghers syndrome

E. Cowden syndrome