Devita, Hellman, and Rosenberg's Cancer

LWBK1006-17 LWW-Govindan-Review December 7, 2011 21:14

Chapter 17•Cancer of the Head and Neck 197

Question 17.9. A 54-year-old woman recently had a resection of a squamous cell cancer

of the supraglottis with bilateral neck dissections. The pathology shows

a T2 lesion, which was completely excised with negative margins but

perivascular and perineural invasion. There are 2 of 28 positive lymph

nodes with extracapsular extension on the right and no positive lymph

nodes. What is the most appropriate primary therapy for this patient?

A. Observation

B. Radiation

C. Chemoradiation

Question 17.10. All of the following are true regarding the addition of cetuximab to defini-

tive radiation in patients with SCCHN, EXCEPT:

A. Results in improved survival compared to radiation alone.

B. Concurrent cetuximab has been proven to be equally effective to

concurrent cisplatin with radiation.

C. Addition of cetuximab results in increased incidence of acne and infu-

sion reactions.

D. No significant difference in the incidence of mucositis between

patients receiving radiation alone or concurrent radiation and cetux-

imab.

Question 17.11. Which of the following statements is FALSE?

A. Radiation therapy alone for locally advanced squamous cell cancer

of the larynx has a lower overall survival than concurrent chemora-

diation.

B. Concurrent chemoradiation allows for better local control than radi-

ation alone for squamous cell cancer of the larynx.

C. A total laryngectomy may not be necessary for the treatment of laryn-

geal cancer.

D. Large-volume laryngeal tumors are best treated with surgery.

Question 17.12. True or False: There is an overall survival benefit from adjuvant chemo-

therapy after resection of a squamous cell cancer of the larynx.

A. True

B. False

Question 17.13. Which of the following statements is FALSE?

A. The three subtypes of nasopharyngeal carcinoma are World Health

Organization (WHO) type I, squamous cell carcinoma; WHO type

II, nonkeratinizing carcinoma; and WHO type III, undifferentiated

carcinoma or lymphoepithelioma.

B. Most nasopharyngeal carcinomas are treated with surgery.

C. Common presenting symptoms of nasopharyngeal carcinomas

include painless upper neck mass, nasal stuffiness, facial pain, and

headache.

D. The majority of nasopharyngeal carcinomas are metastatic to neck

lymph nodes at presentation.