Devita, Hellman, and Rosenberg's Cancer

LWBK1006-23 LWW-Govindan-Review December 12, 2011 19:10

322 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology Review

Question 23.2.35.This patient has a beta-human chorionic gonadotropin (hCG) of 122,300

and undergoes therapy with a suction D&C. Final pathology confirms the

diagnosis of complete hydatidiform mole. The patient is followed with

the following:

A. CT scan every 3 months

B. Ultrasound of the pelvis every 3 months

C. Pelvic examination with PAP smear every 6 weeks

D. Beta-hCG weekly

Question 23.2.36.This patient goes on to develop evidence of persistent GTN. You are

concerned she may have “phantom” hCG. All of the following are correct

regarding “phantom” hCG, EXCEPT:

A. False-positive hCG test results are caused by the presence of het-

erophile antibodies.

B. False-positive hCG results have caused inappropriate therapies to be

performed, including surgery and chemotherapy.

C. Phantom hCG is no longer a problem with modern testing equipment.

D. A urinary beta-hCG assay should be performed.

Question 23.2.37.After a complete metastatic workup, the patient is determined to have

low-risk disease. You recommend the following chemotherapy:

A. Etoposide

B. Vincristine

C. Methotrexate

D. Cyclophosphamide