LWBK1006-24 LWW-Govindan-Review December 12, 2011 19:15
Chapter 24•Cancer of the Breast 333Question 24.11. The Gail model includes all of the following risk factors, EXCEPT:
A. First-degree relatives with breast cancer
B. Previous breast biopsies
C. Age at menarche
D. Age at menopauseQuestion 24.12. You are advising a 42-year-old premenopausal woman with a history of
atypical hyperplasia on prevention strategies. Which of the following is
CORRECT?
A. Tamoxifen reduces her risk by∼50%.
B. Oophorectomy reduces her risk by∼50% to 65%.
C. Bilateral mastectomy completely eliminates her risk of breast cancer.
D. Raloxifene would provide similar benefit as tamoxifen.Question 24.13. A 58-year-old woman presents to your office with a new palpable breast
mass; a biopsy has been recommended based on the results of mammo-
gram and ultrasound. In discussing the options, you explain that:
A. A biopsy can be deferred if a breast MRI does not show significant
enhancement.
B. The false-negative rate of core biopsy is 5% to 10%.
C. Diagnosis by core biopsy decreases the number of surgical procedures
required, even in women ultimately found to have cancer.
D. A fine-needle biopsy can distinguish DCIS from invasive cancer.Question 24.14. You are asked to advise a woman who underwent core-needle biopsy for
evaluation of suspicious microcalcifications detected on screening mam-
mogram. A surgical biopsy should be recommended in all of the following,
EXCEPT:
A. Ductal hyperplasia without atypia, calcifications are seen associated
with the hyperplasia
B. Radial scar
C. Lobular carcinoma in situ
D. Sclerosing adenosis, no calcifications are identified in the specimenQuestion 24.15. All of the following statements about DCIS are true, EXCEPT:
A. DCIS accounts for 15% to 30% of mammographically detected can-
cers.
B. DCIS is most common in premenopausal women.
C. Younger women have a higher rate of local recurrence after breast-
conserving therapy.
D. Preoperative MRI does not improve surgical planning.