Devita, Hellman, and Rosenberg's Cancer

LWBK1006-24 LWW-Govindan-Review December 12, 2011 19:15

Chapter 24•Cancer of the Breast 339

Question 24.41. Which of the following regarding locally advanced breast cancer is

TRUE?

A. Chemotherapy given in the adjuvant setting obviates the need for

postmastectomy radiation.

B. Hormonal therapy does not improve outcome.

C. There is no difference in outcomes regardless of whether chemother-

apy is given in the neoadjuvant or the adjuvant setting.

D. Surgery should be done first to debulk disease and achieve local con-

trol.

Question 24.42. Which of the following does NOT accurately characterize inflammatory

breast cancer (IBC)?

A. Almost all women with IBC have lymph node involvement.

B. The 10-year survival rate exceeds 30%.

C. IBC is staged as T4d, overall stage IIIC.

D. Dermal lymphatic invasion must be seen on biopsy to confirm

IBC.

Question 24.43. With regard to the clinical and pathologic characteristics of male breast

cancer, which of the following is FALSE?

A. Male breast cancer is found, more often than female breast cancer,

to be estrogen-receptor positive, and the older a man is with breast

cancer, the more likely the cancer is estrogen-receptor positive.

B. Both lobular carcinoma in situ and invasive lobular carcinoma have

been reported in male patients.

C. The most common presenting symptom is a painless, firm subareolar

mass, seen in more than 75% of patients.

D. In addition to a palpable mass, common physical examination find-

ings include changes in the areola with nipple retraction, inversion or

fixation, or eczematous skin changes.

Question 24.44. Concerning the staging and treatment of male breast cancer, which of the

following is FALSE?

A. The same TNM staging system is used to stage male breast cancer.

B. Stage and axillary node status are the more important prognostic

indicators in male breast cancer.

C. In cases of DCIS in men, simple mastectomy with axillary node dis-

section is the treatment of choice.

D. For localized disease, a simple mastectomy, or modified radical mas-

tectomy, with local radiation treatment is an effective therapy; there

are no data to suggest that more extensive surgical resection improves

survival.