LWBK1006-29 LWW-Govindan-Review December 9, 2011 15:36
402 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology ReviewQuestion 29.47. Which of the following statements is NOT true?
A. Gonadal tumors are commonly germ cell tumors in adults.
B. Extragonadal germ cell tumors are more frequent in adults than in
children.
C. The sacrococcygeal region is the most common site for extragonadal
germ cell tumors in children.
D. Extragonadal germ cell tumors may involve the pineal gland, medi-
astinum, vagina, or retroperitoneum.Question 29.48. Which of the following is NOT a variety of germ cell tumor?
A. Teratoma or teratocarcinoma
B. Seminomas or dysgerminomas
C. Embryonal carcinoma
D. CholangiocarcinomaQuestion 29.49. Which of the following statements about germ cell tumors is NOT true?
A. Staging should include CT or MRI scans of the mass and the lymph
node region involved, the chest for metastatic disease, a bone scan,
and tumor markers.
B. A transscrotal biopsy of a testicular mass should be performed to
confirm the diagnosis of a germ cell tumor.
C. Cisplatinum-based chemotherapy (cisplatin, vinblastine, and bleo-
mycin [PVB] or cisplatin, etoposide, and bleomycin [PEB]) has
resulted in excellent survival, even in advanced-stage disease in chil-
dren but does not need to be considered in completely resected pedi-
atric germ cell tumors, especially if tumor markers such as AFP return
to normal.
D. Radiation therapy is indicated as second-line therapy for patients who
have relapsed after surgery and chemotherapy.Question 29.50. Which of the following pediatric germ cell tumors would be characterized
as low risk?
A. A localized completely resected testicular tumor by high inguinal
orchiectomy
B. An ovarian tumor that is completely resected and with only micro-
scopic residual disease
C. An extragonadal germ cell tumor that has metastasized only to locally
draining lymph nodes
D. An extragonadal germ cell tumor that is fully resected with only
microscopic residual disease