LWBK1006-02 LWW-Govindan-Review November 24, 2011 11:18
24 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology ReviewQuestion 2.45. The drug vemurafenib (PLX4032) targets which gene in MAPK/ERK
pathway?
A. RAS
B. BRAF
C. BIM
D. ERKQuestion 2.46. Which of the following agents targets tumor metabolic pathways?
A. Pemetrexed
B. Cytarabine
C. Temsirolimus
D. All of the above