Devita, Hellman, and Rosenberg's Cancer

LWBK1006-38 LWW-Govindan-Review December 12, 2011 20:29

CHAPTER 38

IMMUNOSUPPRESSION-RELATED

MALIGNANCIES

LEE RATNER

DIRECTIONS Each of the numbered items below is followed by lettered answers. Select the

ONE lettered answer that is BEST in each case unless instructed otherwise.

QUESTIONS

Question 38.1. In human immunodeficiency virus (HIV)-infected patients, which of the

following malignancies is considered to be an acquired immunodeficiency

syndrome (AIDS)-defining cancer?

A. Colon cancer

B. Cervical cancer

C. Anal cancer

D. Penile cancer

Question 38.2. Chemotherapy is usually well tolerated with concomitant highly active

antiretroviral therapy (HAART) with which of the following exceptions:

A. Zidovudine, nucleotide reverse transcriptase inhibitor therapy

B. Protease inhibitors

C. Raltegravir, the new integrase inhibitor

D. Fuzeon, the HIV entry inhibitor

Question 38.3. What is the response rate to HAART therapy, in a treatment-na ̈ıve patient

with favorable-risk Kaposi sarcoma (KS)?

A. 20%

B. 40%

C. 60%

D. 80%

Corresponding Chapters inCancer: Principles & Practice of Oncology,Ninth Edition: 141 (AIDS-Related Malig-

nancies) and 142 (Transplantation-Related Malignancies).

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