Devita, Hellman, and Rosenberg's Cancer

LWBK1006-40 LWW-Govindan-Review December 12, 2011 20:33

510 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology Review

Question 40.4. Which of the following is an appropriate indication for operative man-

agement of femoral metastases?

A. Size≥2cm

B. Subtrochanteric location of metastases

C. Metastasis involving 40% of the diameter of the cortex

D. All of the above

Question 40.5. Which of the following cancers rarely metastasizes to the brain?

A. Colorectal cancer

B. Melanomas

C. Thyroid cancer

D. Prostate cancer

Question 40.6. Which of the following malignancies has the best long-term survival out-

comes after resection of lung metastases?

A. Sarcomas

B. Melanomas

C. Breast cancer

D. Germ cell tumors

Question 40.7. All of the following statements related to whole brain radiation therapy

(WBRT) are true, EXCEPT:

A. The hippocampus is the least sensitive area of the brain to the effects

of radiation.

B. Myringotomy may be required in some patients to relieve radiation-

induced fluid buildup behind the tympanic membrane.

C. Treatment with whole brain radiation results in complete resolution

of brain metastases in a third of patients with small cell lung carci-

noma.

D. Long-term side effects include dementia and cognitive problems.

Question 40.8. All of the following factors are associated with improved median survival

in patients with brain metastases, EXCEPT:

A. Karnofsky Performance Status of 70% or greater

B. Controlled primary tumor

C. Age less than 65 years old

D. Presence of extra-cranial metastasis

Question 40.9. Overall median survival for patients with malignant pericardial effusion

is:

A. Less than 1 year

B. Less than 9 months

C. Less than 6 months

D. Less than 3 months