Devita, Hellman, and Rosenberg's Cancer

LWBK1006-41 LWW-Govindan-Review November 24, 2011 11:29

518 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology Review

Question 41.5. A 55-year-old man with a 50 pack-year history of smoking presents with

a 6-month history of a cough, 20 pound weight loss, progressive proxi-

mal muscle weakness, and darkening of his skin. Laboratory studies are

remarkable for a low potassium level of 2.9 mEq/dL. Chest X-ray reveals

a right upper lobe mass. What is the most likely finding on biopsy of this

mass?

A. Adenocarcinoma

B. Mesothelioma

C. Small cell carcinoma

D. Squamous cell carcinoma

Question 41.6. In addition to potassium supplementation, which of the following is the

most appropriate treatment for his weakness and hypokalemia?

A. Aminoglutethimide

B. Mitotane

C. Ketoconazole

D. Metyrapone

Question 41.7. Laboratory findings of SIADH include all of the following, EXCEPT:

A. Normal volume status

B. Plasma osmolality greater than urine osmolality

C. Elevated renal excretion of sodium

D. Hyponatremia

Question 41.8. Which of the following tumors is associated with necrolytic migratory

erythema?

A. Gastric cancer

B. Glucagonoma

C. Insulinoma

D. Gastrointestinal (GI) stromal tumor

Question 41.9. Which of the following tumors is most frequently associated with ery-

throcytosis?

A. Adrenal cortical tumors

B. Virilizing ovarian tumors

C. Hepatoma

D. Renal cell carcinoma

Question 41.10. Which laboratory findings would describe the most common anemia seen

in patients with cancer?

A. Low serum iron, low ferritin, elevated total iron-binding capacity

(TIBC), elevated erythropoietin

B. Low serum iron, normal ferritin, elevated TIBC, low erythropoietin

C. Low serum iron, elevated ferritin, low TIBC, low erythropoietin

D. Normal serum iron, elevated ferritin, low TIBC, elevated erythro-

poietin