Devita, Hellman, and Rosenberg's Cancer

LWBK1006-41 LWW-Govindan-Review November 24, 2011 11:29

Chapter 41•Paraneoplastic Syndromes 523

tumors are associated with elevated erythropoietin levels. In the case of

adrenal cortical tumors and virilizing ovarian tumors, the production of

androgenic hormones and prostaglandins leads to erythrocytosis.

Answer 41.10. The answer is C.

Anemia of chronic disease is the most common anemia seen in patients

with cancer and is reflected by a low serum iron, normal or increased

ferritin, low TIBC, and low serum erythropoietin.

Answer 41.11. The answer is D.

Cold agglutinin disease is most common in Waldenstrom’s macroglobu- ̈

linemia.

Answer 41.12. The answer is A.

Male gender is an independent risk factor for DIC.

Answer 41.13. The answer is C.

Focal and segmental glomerulosclerosis is associated with CLL, T-cell

receptor lymphomas, and acute myelogenous leukemias, whereas stom-

ach cancer is associated with membranous nephropathy.

Answer 41.14. The answer is A.

Squamous cell cancers of the lung and head and neck are more commonly

associated with hypercalcemia than the other subtypes.

Answer 41.15. The answer is B.

Pachydermoperiostosis is most often associated with bronchogenic carci-

noma.

Answer 41.16. The answer is C.

Pyoderma gangrenosum is associated with hematological malignancies,

as well as gastric carcinoma and other GI abnormalities.

Answer 41.17. The answer is B.

This describes a Pel-Ebstein fever, which although uncommon, should

lead one to look for Hodgkin’s lymphoma.

Answer 41.18. The answer is D.

Acquired von Willebrand’s disease is seen in plasma cell dyscrasias, gastric

and adrenal carcinomas, leukemias, and lymphomas.

Answer 41.19. The answer is D.

Cancer-related thrombosis occurs due to a complex imbalance between

coagulation and fibrinolysis. Decreased levels of protein C, protein S, and

antithrombin contribute to the prothrombotic state. Increased platelet